Impact of bisphosphonate use as a risk factor for osteonecrosis of the jaws in patients with dental implants

Objective: To determine and report the frequency of osteonecrosis of the jaws (ONJ) in dental publications describing cases involving implants in patients receiving bisphosphonate (BP) therapy. Materials and Methods: An analysis and selection of scientific publications reporting the relationship amo...

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Detalles Bibliográficos
Autores: Ahumada Hernández, Rocío del Carmen, Silva Cruz, Rocío
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:Ecuador
Institución:Universidad Central del Ecuador
Repositorio:Revista Odontología
Idioma:español
OAI Identifier:oai:revistadigital.uce.edu.ec:article/9815
Acceso en línea:https://revistadigital.uce.edu.ec/index.php/odontologia/article/view/9815
Access Level:acceso abierto
Palabra clave:Implantes dentales
Terapia con bisfosfonatos
Osteoporosis
Osteonecrosis de los maxilares
Dental Implants
Bisphosphonate Therapy
Osteonecrosis of the Jaws
Descripción
Sumario:Objective: To determine and report the frequency of osteonecrosis of the jaws (ONJ) in dental publications describing cases involving implants in patients receiving bisphosphonate (BP) therapy. Materials and Methods: An analysis and selection of scientific publications reporting the relationship among ONJ, dental implants, and BP therapy was conducted. Results: Implant placement is considered to represent a 3.9 % risk for the development of ONJ in patients undergoing BP therapy. The occurrence of ONJ has been associated with the dose and duration of BP administration, with a frequency ranging from 0.001% to 0.01 %. Conclusion: Although the frequency of ONJ associated with implant loss in patients using BPs is low, it remains a topic of interest because of its health implications for the individual, including implant loss and partial or total loss of the jaws. Therefore, it is essential to develop skills in anamnesis and in the identification of clinical data that may indicate risks of ONJ.