Bisphosphonate-Induced Osteonecrosis of the Jaw: Case Report

The jaws osteonecrosis induced by bisphosphonates is the first late complication of therapy with bisphosphonates described in scientific literature. This is defined as the development of necrotic bone in the oral cavity of a patient who is receiving treatment with bisphosphonates and did not receive...

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Detalhes bibliográficos
Autores: Caldas, Rogério Jardim, Pontes, José Roberto de Menezes, Antunes, Héliton Spíndola
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2009
País:Brasil
Recursos:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
Repositório:Revista Brasileira de Cancerologia (Online)
Idioma:português
OAI Identifier:oai:rbc.inca.gov.br:article/1645
Acesso em linha:https://rbc.inca.gov.br/index.php/revista/article/view/1645
Access Level:Acceso aberto
Palavra-chave:Osteonecrose
Maxilares
Bisfosfonatos
Osteonecrosis
Jaw
Bisphosphonates
Descrição
Resumo:The jaws osteonecrosis induced by bisphosphonates is the first late complication of therapy with bisphosphonates described in scientific literature. This is defined as the development of necrotic bone in the oral cavity of a patient who is receiving treatment with bisphosphonates and did not receive radiotherapy in the head or neck region. Clinically, the lesions are characterized as ulceration of the oral mucosa, which is often very painful, and exposes the underlying bone. This paper reports a case of osteonecrosis induced by bisphosphonates of spontaneous surging, difficult to respond to conservative treatment, then achieving a cure with surgery.