Multiple myeloma associated with a secondary amyloidosis. Report of one case

Multiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and l...

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Detalhes bibliográficos
Autores: Rodríguez-Lagos FA, Sorlí JV, Calviño-Naveira MC, Capell NE
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Recursos:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p3290
Acesso em linha:https://fisabio.portalinvestigacion.com/publicaciones/3290
Access Level:acceso abierto
Palavra-chave:Amyloidosis
Congo Red
Multiple Myeloma
Plasma Cells
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spelling Multiple myeloma associated with a secondary amyloidosis. Report of one caseRodríguez-Lagos FASorlí JVCalviño-Naveira MCCapell NEAmyloidosisCongo RedMultiple MyelomaPlasma CellsMultiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and lambda light chains. These results motivated her derivation to hematology: her serum calcium was 11.8 mg/dl, immunofluorescence showed a monoclonal component of lambda chains and urine Bence-Jones protein was positive. A bone marrow biopsy confirmed plasma cell infiltration. A Congo-red stain of a rectal biopsy was positive. The patient was treated with thalidomide, bortezomid and dexamethasone.SOC MEDICA SANTIAGO2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/3290REVISTA MEDICA DE CHILEISSN: 00349887ISSNe: 07176163reponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Españolinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p32902026-06-11T12:45:17Z
dc.title.none.fl_str_mv Multiple myeloma associated with a secondary amyloidosis. Report of one case
title Multiple myeloma associated with a secondary amyloidosis. Report of one case
spellingShingle Multiple myeloma associated with a secondary amyloidosis. Report of one case
Rodríguez-Lagos FA
Amyloidosis
Congo Red
Multiple Myeloma
Plasma Cells
title_short Multiple myeloma associated with a secondary amyloidosis. Report of one case
title_full Multiple myeloma associated with a secondary amyloidosis. Report of one case
title_fullStr Multiple myeloma associated with a secondary amyloidosis. Report of one case
title_full_unstemmed Multiple myeloma associated with a secondary amyloidosis. Report of one case
title_sort Multiple myeloma associated with a secondary amyloidosis. Report of one case
dc.creator.none.fl_str_mv Rodríguez-Lagos FA
Sorlí JV
Calviño-Naveira MC
Capell NE
author Rodríguez-Lagos FA
author_facet Rodríguez-Lagos FA
Sorlí JV
Calviño-Naveira MC
Capell NE
author_role author
author2 Sorlí JV
Calviño-Naveira MC
Capell NE
author2_role author
author
author
dc.subject.none.fl_str_mv Amyloidosis
Congo Red
Multiple Myeloma
Plasma Cells
topic Amyloidosis
Congo Red
Multiple Myeloma
Plasma Cells
description Multiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and lambda light chains. These results motivated her derivation to hematology: her serum calcium was 11.8 mg/dl, immunofluorescence showed a monoclonal component of lambda chains and urine Bence-Jones protein was positive. A bone marrow biopsy confirmed plasma cell infiltration. A Congo-red stain of a rectal biopsy was positive. The patient was treated with thalidomide, bortezomid and dexamethasone.
publishDate 2018
dc.date.none.fl_str_mv 2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/3290
url https://fisabio.portalinvestigacion.com/publicaciones/3290
dc.language.none.fl_str_mv Español
language_invalid_str_mv Español
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv SOC MEDICA SANTIAGO
publisher.none.fl_str_mv SOC MEDICA SANTIAGO
dc.source.none.fl_str_mv REVISTA MEDICA DE CHILE
ISSN: 00349887
ISSNe: 07176163
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
collection r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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