Oral amyloidosis: an update
Background Amyloidosis is a disease characterized by the progressive deposition of abnormal proteins that can occur in any organ. In the oral cavity, the tongue is the most common affected site, usually causing macroglossia. Biopsy is essential for the diagnosis and the occurrence of its systemic fo...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2023 |
| País: | Brasil |
| Institución: | Universidade Federal de Minas Gerais (UFMG) |
| Repositorio: | Repositório Institucional da UFMG |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.ufmg.br:1843/82433 |
| Acceso en línea: | https://doi.org/10.4317/medoral.25761 http://hdl.handle.net/1843/82433 https://orcid.org/0000-0003-3348-4403 https://orcid.org/0000-0002-6657-4547 https://orcid.org/0000-0001-9125-6631 https://orcid.org/0000-0002-9179-0145 https://orcid.org/0000-0001-7220-1360 https://orcid.org/0000-0001-6677-0065 https://orcid.org/0000-0001-9623-7835 https://orcid.org/0000-0002-6691-3764 |
| Access Level: | acceso abierto |
| Palabra clave: | Amyloidosis mouth Congo red Proteins Mouth Tongue Multiple myeloma Prevalence Prognosis Therapeutics Macroglossia Diagnosis Biopsy |
| Sumario: | Background Amyloidosis is a disease characterized by the progressive deposition of abnormal proteins that can occur in any organ. In the oral cavity, the tongue is the most common affected site, usually causing macroglossia. Biopsy is essential for the diagnosis and the occurrence of its systemic form is mandatory to be investigated. This systematic review evaluated the existing information in the literature on Amyloidosis in the oral cavity to allow a more comprehensive and updated analysis of its clinicopathological characteristics, as well as to explore the main forms of treatment and prognostic factors. Material and Methods Electronic searches were undertaken in five databases supplemented by manual scrutiny. Results A total of 111 studies were included with 158 individuals. Conclusions The disease had a higher prevalence in women, the tongue was the most affected site, as well as the systemic form of the disease. The worst prognosis was for cases of systemic amyloidosis associated with multiple myeloma |
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