Recent impact of microfluidics on skin models for perspiration simulation
Skin models offer an in vitro alternative to human trials without their high costs, variability, and ethical issues. Perspiration models, in particular, have gained relevance lately due to the rise of sweat analysis and wearable technology. The predominant approach to replicate the key features of p...
| Authors: | , , |
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| Format: | article |
| Publication Date: | 2021 |
| Country: | España |
| Institution: | Universitat Politècnica de Catalunya (UPC) |
| Repository: | UPCommons. Portal del coneixement obert de la UPC |
| Language: | English |
| OAI Identifier: | oai:upcommons.upc.edu:2117/352926 |
| Online Access: | https://hdl.handle.net/2117/352926 https://dx.doi.org/10.3390/membranes11020150 |
| Access Level: | Open access |
| Keyword: | Skin Perspiration Wearable technology Electronic instruments Skin models Skin phantom Artificial skin Sweat Wearables In vitro testing Pell Perspiració Electrònica -- Aparells i instruments Dispositius microfluidics Àrees temàtiques de la UPC::Enginyeria mecànica |
| Summary: | Skin models offer an in vitro alternative to human trials without their high costs, variability, and ethical issues. Perspiration models, in particular, have gained relevance lately due to the rise of sweat analysis and wearable technology. The predominant approach to replicate the key features of perspiration (sweat gland dimensions, sweat rates, and skin surface characteristics) is to use lasermachined membranes. Although they work effectively, they present some limitations at the time of replicating sweat gland dimensions. Alternative strategies in terms of fabrication and materials have also showed similar challenges. Additional research is necessary to implement a standardized, simple, and accurate model representing sweating for wearable sensors testing |
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