Recent impact of microfluidics on skin models for perspiration simulation

Skin models offer an in vitro alternative to human trials without their high costs, variability, and ethical issues. Perspiration models, in particular, have gained relevance lately due to the rise of sweat analysis and wearable technology. The predominant approach to replicate the key features of p...

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Detalles Bibliográficos
Autores: Rabost Garcia, Genís|||0000-0002-6783-4400, Farré Lladós, Josep|||0000-0001-5909-0176, Casals Terré, Jasmina|||0000-0002-1368-3950
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/352926
Acceso en línea:https://hdl.handle.net/2117/352926
https://dx.doi.org/10.3390/membranes11020150
Access Level:acceso abierto
Palabra clave:Skin
Perspiration
Wearable technology
Electronic instruments
Skin models
Skin phantom
Artificial skin
Sweat
Wearables
In vitro testing
Pell
Perspiració
Electrònica -- Aparells i instruments
Dispositius microfluidics
Àrees temàtiques de la UPC::Enginyeria mecànica
Descripción
Sumario:Skin models offer an in vitro alternative to human trials without their high costs, variability, and ethical issues. Perspiration models, in particular, have gained relevance lately due to the rise of sweat analysis and wearable technology. The predominant approach to replicate the key features of perspiration (sweat gland dimensions, sweat rates, and skin surface characteristics) is to use lasermachined membranes. Although they work effectively, they present some limitations at the time of replicating sweat gland dimensions. Alternative strategies in terms of fabrication and materials have also showed similar challenges. Additional research is necessary to implement a standardized, simple, and accurate model representing sweating for wearable sensors testing