Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update

Ginseng, a medicinal plant of the genus Panax, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popul...

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Bibliographic Details
Authors: Valdes-Gonzalez, Jose Antonio, Sánchez Gómez-Serranillos, Marta, Moratilla-Rivera, Ignacio, Iglesias Peinado, Irene, Gómez-Serranillos Cuadrado, María Pilar
Format: article
Publication Date:2023
Country:España
Institution:Universidad Complutense de Madrid (UCM)
Repository:Docta Complutense
Language:English
OAI Identifier:oai:docta.ucm.es:20.500.14352/125238
Online Access:https://hdl.handle.net/20.500.14352/125238
Access Level:Open access
Keyword:615.011
615.4
58
Ginsenosides
Ginseng
Immunomodulation
Anti-inflammatory
Anti-cancer
Saponins
Polysaccharides
Farmacología (Farmacia)
Tecnología farmaceútica
Botánica (Farmacia)
Bioquímica (Farmacia)
3209 Farmacología
3209.05 Farmacognosia
Description
Summary:Ginseng, a medicinal plant of the genus Panax, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popular as a remedy for fatigue and asthenia. This review provides an update on current research pertaining to ginseng and its isolated compounds, namely, ginsenosides and polysaccharides. The primary focus is on three crucial pharmacological activities, namely, immunomodulation, anti-inflammatory, and anti-cancer effects. The review encompasses studies on both isolated compounds and various ginseng extracts obtained from the root, leaves, and berries.