Visualising the membrane viscosity of porcine eye lens cells using molecular rotors

The plasma membranes of cells within the eye lens play an important role in metabolite transport within the avascular tissue of the lens, maintaining its transparency over the entire lifespan of an individual. Here we use viscosity-sensitive ‘molecular rotors’ to map the microscopic viscosity within...

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Bibliographic Details
Authors: Peter S. S, Peter S. herin, López Duarte, Ismael, Dent, Michael R., Markéta Kubánková, Vyšniauskas, Aurimas, Bull, James A., Reshetnikova, Evdokiya S., Klymchenko, Andrey S., Tsentalovich, Yuri P., Kuimova, Marina K.
Format: article
Publication Date:2017
Country:España
Institution:Universidad Complutense de Madrid (UCM)
Repository:Docta Complutense
Language:English
OAI Identifier:oai:docta.ucm.es:20.500.14352/114903
Online Access:https://hdl.handle.net/20.500.14352/114903
Access Level:Open access
Keyword:615.31
615:54
Química farmaceútica
23 Química
Description
Summary:The plasma membranes of cells within the eye lens play an important role in metabolite transport within the avascular tissue of the lens, maintaining its transparency over the entire lifespan of an individual. Here we use viscosity-sensitive ‘molecular rotors’ to map the microscopic viscosity within these unusual cell membranes, establishing that they are characterised by an unprecedentedly high degree of lipid organisation.

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