Prevalence of High Blood Pressure in Pediatric Patients with Sleep-Disordered Breathing, Reversibility after Treatment: The KIDS TRIAL Study Protocol

Current data support an increase in the prevalence of high blood pressure (HBP) in pediatric patients with sleep-disordered breathing (SDB). Adeno-tonsillectomy has been shown to be an effective treatment for most patients. Our objective was to determine the prevalence of HBP in pediatric patients w...

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Detalles Bibliográficos
Autores: Castillo García, María, Solano Pérez, Esther, Romero Peralta, Sofía, Viejo Ayuso, María Esther, Silgado Martínez, Laura, Álvarez Balado, Leticia, Mediano San Andrés, Rosa, Resano, Pilar, Cano-Pumarega, Irene, Sánchez de la Torre, Manuel, Ortigado, Alfonso, López Dueñas, Ana, Fidalgo, Laura, Rodríguez, Ángel, Mediano, Olga
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10459.1/463256
Acceso en línea:https://doi.org/10.3390/children9121849
https://hdl.handle.net/10459.1/463256
Access Level:acceso abierto
Palabra clave:Sleep-disordered breathing
High blood pressure
Sleep apnea
Children
Cardiovascular risk
Adeno-tonsillectomy
Descripción
Sumario:Current data support an increase in the prevalence of high blood pressure (HBP) in pediatric patients with sleep-disordered breathing (SDB). Adeno-tonsillectomy has been shown to be an effective treatment for most patients. Our objective was to determine the prevalence of HBP in pediatric patients with SDB and the impact of adeno-tonsillectomy with a multicenter, longitudinal, and prospective study that included 286 children referred for suspected SDB. The diagnosis of SDB was established by polysomnography (PSG) and the diagnosis of HBP by 24-h ambulatory blood pressure monitoring (ABPM). In patients without SDB and SDB without treatment indication, these tests were repeated six months after the baseline visit. For patients with medical treatment for SDB, the tests were repeated six months after the treatment initiation. Finally, in patients with surgery indication, ABPM was performed just before surgical treatment and ABPM and PSG six months after the intervention. The study contributes to elucidating the association between SDB and HBP in pediatric patients. Moreover, it contributes to determining if intervention with adeno-tonsillectomy is associated with BP reduction. The results have direct implications for the management of SDB, providing essential information on treatment indications for existing clinical guidelines. NCT03696654.

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