Free radical scavenging activity of Pterogyne nitens Tul. (Fabaceae)

As part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphen...

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Detalhes bibliográficos
Autores: Regasini, Luis Octávio [UNESP], De Oliveira, Camila Martins [UNESP], Vellosa, José Carlos Rebuglio [UNESP], Oliveira, Olga Maria Mascarenhas De Faria [UNESP], Silva, Dulce Helena Siqueira [UNESP], Bolzani, Vanderlan Da Silva [UNESP]
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2008
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositório:Repositório Institucional da UNESP
Idioma:inglês
OAI Identifier:oai:repositorio.unesp.br:11449/225390
Acesso em linha:http://hdl.handle.net/11449/225390
Access Level:Acceso aberto
Palavra-chave:ABTS
Antioxidant
Caesalpinioideae
DPPH
Fabaceae
Flavonoid
Flavonol
Free radical scavenging activity
Leguminosae
Pterogyne nitens
Descrição
Resumo:As part of our ongoing research on antioxidant agents from Brazilian flora, twenty extracts and fractions obtained from Pterogyne nitens Tulasne (Fabaceae) were screened for free radical scavenging activity by using ABTS [2,2′-azinobis(3-ethylenebenzothiazoline-6-sulfonic acid)] and DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) radicals colorimetric assay and β-carotene bleaching test. The strongest activity was found in ethyl acetate fraction from the stem barks, exhibiting IC50 values (in μg/ml) of 2.10 ± 0.1 and 10.2 ± 0.3 on ABTS•+ and DPPH•, respectively. Additionally, chromatographic fractionation of stem barks yielding myricetin, quercitrin and mirycetrin, three flavonols with remarkable antioxidant activity. © 2008 Academic Journals.

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