Cholangiocarcinoma in an American Rhea (Rhea Americana araneipes)

Cholangiocarcinomas are neoplasms that originate from the bile duct epithelium. The present case described a cholangiocarcinoma in an adult female American Rhea (Rhea Americana araneipes) by means of gross, histopathology and immunohistochemistry. Irregular, firm, multifocal, yellow-white masses, me...

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Detalhes bibliográficos
Autores: Rocha, Paulo Ricardo Dell'armelina [UNESP], Lopes, Letícya Lerner, Arruda, Laura Peixoto de, Pescador, Caroline Argenta, Cruz, Raquel Aparecida Sales da, Colodel, Edson Moleta
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2015
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositório:Repositório Institucional da UNESP
Idioma:inglês
OAI Identifier:oai:repositorio.unesp.br:11449/132310
Acesso em linha:http://dx.doi.org/10.1590/0103-8478cr20140822
http://hdl.handle.net/11449/132310
Access Level:Acceso aberto
Palavra-chave:Cholangiocarcinoma
Rhea
Immunohistochemistry
Wildlife
Colangiocarcinoma
Ema
Imuno-histoquímica
Aves selvagens
Descrição
Resumo:Cholangiocarcinomas are neoplasms that originate from the bile duct epithelium. The present case described a cholangiocarcinoma in an adult female American Rhea (Rhea Americana araneipes) by means of gross, histopathology and immunohistochemistry. Irregular, firm, multifocal, yellow-white masses, measuring from 0.4 to 6cm in diameter were observed in both liver lobes. At the cut surface, multiple firm nodules filled with connective tissue were present. Microscopically, the neoplasia was composed of small, irregular, gland-like structures of neoplastic cells surrounded by connective tissue. The cells resembled epithelial cells of the hepatic biliary ducts. Neoplastic cells were positive for cytokeratin and negative for vimentin. This is the first report of a malignant fatal neoplasia in an American Rhea.