Small calcified lesions suggestive of neurocysticercosis are associated with mesial temporal sclerosis
Recent studies have suggested a possible relationship between temporal lobe epilepsy with mesial temporal sclerosis (MTS) and neurocysticercosis (NC). We performed a case-control study to evaluate the association of NC and MTS. Method: : We randomly selected patients with different epilepsy types, i...
| Autores: | , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2014 |
| País: | Brasil |
| Recursos: | Universidade Estadual Paulista (UNESP) |
| Repositório: | Repositório Institucional da UNESP |
| Idioma: | inglês |
| OAI Identifier: | oai:repositorio.unesp.br:11449/129958 |
| Acesso em linha: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000700510&lng=en&nrm=iso&tlng=en http://hdl.handle.net/11449/129958 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Hippocampal sclerosis Cysticercosis Temporal lobe epilepsy Mesial temporal sclerosis Neurocysticercosis Calcifications Esclerose de hipocampo Cisticercose Epilepsia do lobo temporal Esclerose mesial temporal Neurocisticercose Calcificações |
| Resumo: | Recent studies have suggested a possible relationship between temporal lobe epilepsy with mesial temporal sclerosis (MTS) and neurocysticercosis (NC). We performed a case-control study to evaluate the association of NC and MTS. Method: : We randomly selected patients with different epilepsy types, including: MTS, primary generalized epilepsy (PGE) and focal symptomatic epilepsy (FSE). Patients underwent a structured interview, followed by head computed tomography (CT). A neuroradiologist evaluated the scan for presence of calcified lesions suggestive of NC. CT results were matched with patients'data. Results: : More patients in the MTS group displayed calcified lesions suggestive of NC than patients in the other groups (p=0.002). On multivariate analysis, MTS was found to be an independent predictor of one or more calcified NC lesions (p=0.033). Conclusion: : After controlling for confounding factors, we found an independent association between NC calcified lesions and MTS. |
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