The volume and order of starting exercise modulates the glucose-lowering effect of a single session of combined exercise in middle-aged and older adults with type 2 diabetes

Problem Statement: Although combined exercise (CE) is frequently prescribed for glycemic control of Type 2 Diabetes Mellitus (T2DM) subjects, beginning CE session with aerobic or resistance exercises can lead to distinct responses in capillary glucose, especially when training prescriptions differ i...

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Detalhes bibliográficos
Autores: João G. Silveira-Rodrigues, Dawit Albieiro Pinheiro Gonçalves, Augusto S. A. Correia, Pedro H. M. Ogando, Rodrigo S. Delevatti, Washington Pires, Ivana M. S. Aleixo, Danusa Dias Soares
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2022
País:Brasil
Recursos:Universidade Federal de Minas Gerais (UFMG)
Repositório:Repositório Institucional da UFMG
Idioma:inglês
OAI Identifier:oai:repositorio.ufmg.br:1843/64804
Acesso em linha:https://doi.org/10.7752/jpes.2022.04132
http://hdl.handle.net/1843/64804
https://orcid.org/0000-0003-2621-3330
Access Level:Acceso aberto
Palavra-chave:Concurrent exercise
Blood glucose
Training workload
Exercise volume
Exercise intensity
Diabetes mellitus
Diabetes Mellitus
Exercício Físico
Glicemia
Descrição
Resumo:Problem Statement: Although combined exercise (CE) is frequently prescribed for glycemic control of Type 2 Diabetes Mellitus (T2DM) subjects, beginning CE session with aerobic or resistance exercises can lead to distinct responses in capillary glucose, especially when training prescriptions differ in intensity and volume. Approach: This study aimed to evaluate the effect of exercise intensity, volume, and order within combined exercise sessions on glycemic response. Purpose: Forty T2DM subjects participated in this study. The subjects were divided into three different protocols: standard (S-P, n = 13), high intensity (HI-P, n = 16), and high volume (HV-P, n = 11) in two counter-balanced orders each [i.e., resistance exercise followed by aerobic exercise (R-A) or vice versa (A-R)]. The capillary glucose was evaluated before and after each CE session. Results: All protocols of combined exercise reduced glucose concentrations (p < .001). HV-P induced a glycemic reduction that was 2-fold higher than that observed in HI-P (34% vs. 18%; p < .05). Both exercise orders within combined exercise session reduced glucose concentrations (S-P: 25%, 28%; HI-P: 17%, 19%, and HV-P: 31%, 36% for A-R and R-A, respectively); however, R-A induced slightly larger (Cohen’s d was 13-33% higher in R-A compared to A-R), but clinically relevant, reductions in all combined exercise protocols. Preexercise glucose concentrations were correlated to exercise-induced glucose reduction only in the A-R order (r = 65 to .79, p < .05). Conclusion: All combined exercise protocols were effective in decreasing glucose concentrations. Nonetheless, a higher magnitude of glucose-lowering effect occurred when a higher exercise volume was performed and when performing resistance instead of aerobic exercise in the first place.