Antimicrobial activity of Uncaria tomentosa against oral human pathogens

Uncaria tomentosa is considered a medicinal plant used over centuries by the peruvian population as an alternative treatment for several diseases. Many microorganisms usually inhabit the human oral cavity and under certain conditions can become etiologic agents of diseases. The aim of the present st...

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Autores: Ccahuana-Vasquez, Renzo Alberto, Ferreira dos Santos, Silvana Soléo, Koga-Ito, Cristiane Yumi [UNESP], Cardoso Jorge, Antonio Olavo
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/69482
Acesso em linha:http://dx.doi.org/10.1590/S1806-83242007000100008
http://hdl.handle.net/11449/69482
Access Level:acceso abierto
Palavra-chave:Bacteria
Candida albicans
Cat's claw
Contact inhibition
antiinfective agent
plant extract
bacterium
chemistry
dental caries
drug antagonism
drug effect
drug screening
Enterobacteriaceae
human
isolation and purification
microbiological examination
microbiology
mouth
phytotherapy
Pseudomonas aeruginosa
Staphylococcus
Streptococcus mutans
Uncaria tomentosa
Anti-Bacterial Agents
Cat's Claw
Dental Caries
Drug Evaluation, Preclinical
Humans
Microbial Sensitivity Tests
Mouth
Phytotherapy
Plant Extracts
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spelling Antimicrobial activity of Uncaria tomentosa against oral human pathogensBacteriaCandida albicansCat's clawContact inhibitionantiinfective agentplant extractbacteriumchemistrydental cariesdrug antagonismdrug effectdrug screeningEnterobacteriaceaehumanisolation and purificationmicrobiological examinationmicrobiologymouthphytotherapyPseudomonas aeruginosaStaphylococcusStreptococcus mutansUncaria tomentosaAnti-Bacterial AgentsCat's ClawDental CariesDrug Evaluation, PreclinicalHumansMicrobial Sensitivity TestsMouthPhytotherapyPlant ExtractsUncaria tomentosa is considered a medicinal plant used over centuries by the peruvian population as an alternative treatment for several diseases. Many microorganisms usually inhabit the human oral cavity and under certain conditions can become etiologic agents of diseases. The aim of the present study was to evaluate the antimicrobial activity of different concentrations of Uncaria tomentosa on different strains of microorganisms isolated from the human oral cavity. Micropulverized Uncaria tomentosa was tested in vitro to determine the minimum inhibitory concentration (MIC) on selected microbial strains. The tested strains were oral clinical isolates of Streptococcus mutans, Staphylococcus spp., Candida albicans, Enterobacteriaceae and Pseudomonas aeruginosa. The tested concentrations of Uncaria tomentosa ranged from 0.25-5% in Müeller-Hinton agat. Three percent Uncaria tomentosa inhibited 8% of Enterobacteriaceae isolates, 52% of S. mutans and 96% of Staphylococcus spp. The tested concentrations did not present inhibitory effect on P. aeruginosa and C. albicans. It could be concluded that micropulverized Uncaria tomentosa presented antimicrobial activity on Enterobacteriaceae, S. mutans and Staphylococcus spp. isolates.Department of Physiology Sciences School of Dentistry of Piracicaba State University of Campinas, CampinasDepartment of Microbiology University of Taubaté, Rua dos Operários, 9, Taubaté, SP 12000-000Department of Bioscience and Oral Diagnosis School of Dentistry of São José dos Campos São Paulo State University, São PauloDepartment of Bioscience and Oral Diagnosis School of Dentistry of São José dos Campos São Paulo State University, São PauloUniversidade Estadual de Campinas (UNICAMP)University of TaubatéUniversidade Estadual Paulista (Unesp)2014-05-27T11:22:23Z2014-05-27T11:22:23Z2007-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article46-50application/pdfhttp://dx.doi.org/10.1590/S1806-83242007000100008Brazilian Oral Research, v. 21, n. 1, p. 46-50, 2007.1806-83241807-3107http://hdl.handle.net/11449/6948210.1590/S1806-83242007000100008S1806-832420070001000082-s2.0-341471887512-s2.0-34147188751.pdf005356715362356965435631614034210000-0002-2416-2173Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Oral Research1.223info:eu-repo/semantics/openAccessCcahuana-Vasquez, Renzo AlbertoFerreira dos Santos, Silvana SoléoKoga-Ito, Cristiane Yumi [UNESP]Cardoso Jorge, Antonio Olavo2024-11-07T13:18:34Zoai:repositorio.unesp.br:11449/69482Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-11-07T13:18:34Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Antimicrobial activity of Uncaria tomentosa against oral human pathogens
title Antimicrobial activity of Uncaria tomentosa against oral human pathogens
spellingShingle Antimicrobial activity of Uncaria tomentosa against oral human pathogens
Ccahuana-Vasquez, Renzo Alberto
Bacteria
Candida albicans
Cat's claw
Contact inhibition
antiinfective agent
plant extract
bacterium
chemistry
dental caries
drug antagonism
drug effect
drug screening
Enterobacteriaceae
human
isolation and purification
microbiological examination
microbiology
mouth
phytotherapy
Pseudomonas aeruginosa
Staphylococcus
Streptococcus mutans
Uncaria tomentosa
Anti-Bacterial Agents
Cat's Claw
Dental Caries
Drug Evaluation, Preclinical
Humans
Microbial Sensitivity Tests
Mouth
Phytotherapy
Plant Extracts
title_short Antimicrobial activity of Uncaria tomentosa against oral human pathogens
title_full Antimicrobial activity of Uncaria tomentosa against oral human pathogens
title_fullStr Antimicrobial activity of Uncaria tomentosa against oral human pathogens
title_full_unstemmed Antimicrobial activity of Uncaria tomentosa against oral human pathogens
title_sort Antimicrobial activity of Uncaria tomentosa against oral human pathogens
dc.creator.none.fl_str_mv Ccahuana-Vasquez, Renzo Alberto
Ferreira dos Santos, Silvana Soléo
Koga-Ito, Cristiane Yumi [UNESP]
Cardoso Jorge, Antonio Olavo
author Ccahuana-Vasquez, Renzo Alberto
author_facet Ccahuana-Vasquez, Renzo Alberto
Ferreira dos Santos, Silvana Soléo
Koga-Ito, Cristiane Yumi [UNESP]
Cardoso Jorge, Antonio Olavo
author_role author
author2 Ferreira dos Santos, Silvana Soléo
Koga-Ito, Cristiane Yumi [UNESP]
Cardoso Jorge, Antonio Olavo
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Campinas (UNICAMP)
University of Taubaté
Universidade Estadual Paulista (Unesp)
dc.subject.por.fl_str_mv Bacteria
Candida albicans
Cat's claw
Contact inhibition
antiinfective agent
plant extract
bacterium
chemistry
dental caries
drug antagonism
drug effect
drug screening
Enterobacteriaceae
human
isolation and purification
microbiological examination
microbiology
mouth
phytotherapy
Pseudomonas aeruginosa
Staphylococcus
Streptococcus mutans
Uncaria tomentosa
Anti-Bacterial Agents
Cat's Claw
Dental Caries
Drug Evaluation, Preclinical
Humans
Microbial Sensitivity Tests
Mouth
Phytotherapy
Plant Extracts
topic Bacteria
Candida albicans
Cat's claw
Contact inhibition
antiinfective agent
plant extract
bacterium
chemistry
dental caries
drug antagonism
drug effect
drug screening
Enterobacteriaceae
human
isolation and purification
microbiological examination
microbiology
mouth
phytotherapy
Pseudomonas aeruginosa
Staphylococcus
Streptococcus mutans
Uncaria tomentosa
Anti-Bacterial Agents
Cat's Claw
Dental Caries
Drug Evaluation, Preclinical
Humans
Microbial Sensitivity Tests
Mouth
Phytotherapy
Plant Extracts
description Uncaria tomentosa is considered a medicinal plant used over centuries by the peruvian population as an alternative treatment for several diseases. Many microorganisms usually inhabit the human oral cavity and under certain conditions can become etiologic agents of diseases. The aim of the present study was to evaluate the antimicrobial activity of different concentrations of Uncaria tomentosa on different strains of microorganisms isolated from the human oral cavity. Micropulverized Uncaria tomentosa was tested in vitro to determine the minimum inhibitory concentration (MIC) on selected microbial strains. The tested strains were oral clinical isolates of Streptococcus mutans, Staphylococcus spp., Candida albicans, Enterobacteriaceae and Pseudomonas aeruginosa. The tested concentrations of Uncaria tomentosa ranged from 0.25-5% in Müeller-Hinton agat. Three percent Uncaria tomentosa inhibited 8% of Enterobacteriaceae isolates, 52% of S. mutans and 96% of Staphylococcus spp. The tested concentrations did not present inhibitory effect on P. aeruginosa and C. albicans. It could be concluded that micropulverized Uncaria tomentosa presented antimicrobial activity on Enterobacteriaceae, S. mutans and Staphylococcus spp. isolates.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
2014-05-27T11:22:23Z
2014-05-27T11:22:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1806-83242007000100008
Brazilian Oral Research, v. 21, n. 1, p. 46-50, 2007.
1806-8324
1807-3107
http://hdl.handle.net/11449/69482
10.1590/S1806-83242007000100008
S1806-83242007000100008
2-s2.0-34147188751
2-s2.0-34147188751.pdf
0053567153623569
6543563161403421
0000-0002-2416-2173
url http://dx.doi.org/10.1590/S1806-83242007000100008
http://hdl.handle.net/11449/69482
identifier_str_mv Brazilian Oral Research, v. 21, n. 1, p. 46-50, 2007.
1806-8324
1807-3107
10.1590/S1806-83242007000100008
S1806-83242007000100008
2-s2.0-34147188751
2-s2.0-34147188751.pdf
0053567153623569
6543563161403421
0000-0002-2416-2173
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Oral Research
1.223
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 46-50
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1853671410741805056
score 15,198674

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