Antimicrobial activity of Uncaria tomentosa against oral human pathogens
Uncaria tomentosa is considered a medicinal plant used over centuries by the peruvian population as an alternative treatment for several diseases. Many microorganisms usually inhabit the human oral cavity and under certain conditions can become etiologic agents of diseases. The aim of the present st...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2007 |
| País: | Brasil |
| Institución: | Universidade Estadual Paulista (UNESP) |
| Repositorio: | Repositório Institucional da UNESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unesp.br:11449/69482 |
| Acceso en línea: | http://dx.doi.org/10.1590/S1806-83242007000100008 http://hdl.handle.net/11449/69482 |
| Access Level: | acceso abierto |
| Palabra clave: | Bacteria Candida albicans Cat's claw Contact inhibition antiinfective agent plant extract bacterium chemistry dental caries drug antagonism drug effect drug screening Enterobacteriaceae human isolation and purification microbiological examination microbiology mouth phytotherapy Pseudomonas aeruginosa Staphylococcus Streptococcus mutans Uncaria tomentosa Anti-Bacterial Agents Cat's Claw Dental Caries Drug Evaluation, Preclinical Humans Microbial Sensitivity Tests Mouth Phytotherapy Plant Extracts |
| Sumario: | Uncaria tomentosa is considered a medicinal plant used over centuries by the peruvian population as an alternative treatment for several diseases. Many microorganisms usually inhabit the human oral cavity and under certain conditions can become etiologic agents of diseases. The aim of the present study was to evaluate the antimicrobial activity of different concentrations of Uncaria tomentosa on different strains of microorganisms isolated from the human oral cavity. Micropulverized Uncaria tomentosa was tested in vitro to determine the minimum inhibitory concentration (MIC) on selected microbial strains. The tested strains were oral clinical isolates of Streptococcus mutans, Staphylococcus spp., Candida albicans, Enterobacteriaceae and Pseudomonas aeruginosa. The tested concentrations of Uncaria tomentosa ranged from 0.25-5% in Müeller-Hinton agat. Three percent Uncaria tomentosa inhibited 8% of Enterobacteriaceae isolates, 52% of S. mutans and 96% of Staphylococcus spp. The tested concentrations did not present inhibitory effect on P. aeruginosa and C. albicans. It could be concluded that micropulverized Uncaria tomentosa presented antimicrobial activity on Enterobacteriaceae, S. mutans and Staphylococcus spp. isolates. |
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