Temporal pole signal abnormality on MR imaging in temporal lobe epilepsy with hippocampal sclerosis: a fluid-attenuated inversion-recovery study

OBJECTIVE: To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history. METHOD: Coronal FLAIR images of the temporal...

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Detalles Bibliográficos
Autores: Carrete Junior, Henrique [UNIFESP], Abdala, Nitamar [UNIFESP], Lin, Katia [UNIFESP], Caboclo, Luís Otávio Sales Ferreira [UNIFESP], Centeno, Ricardo Silva [UNIFESP], Sakamoto, Américo Ceiki [UNIFESP], Szejnfeld, Jacob [UNIFESP], Nogueira, Roberto Gomes [UNIFESP], Yacubian, Elza Márcia Targas [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/3878
Acceso en línea:http://dx.doi.org/10.1590/S0004-282X2007000400001
http://repositorio.unifesp.br/handle/11600/3878
Access Level:acceso abierto
Palabra clave:epilepsy
temporal lobe epilepsy
hippocampal sclerosis
temporal pole
magnetic resonance imaging
epilepsia
epilepsia do lobo temporal
esclerose hipocampal
pólo temporal
ressonância magnética
Descripción
Sumario:OBJECTIVE: To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history. METHOD: Coronal FLAIR images of the temporal pole were assessed in 120 patients with HS and in 30 normal subjects, to evaluate gray-white matter demarcation. RESULTS: Ninety (75%) of 120 patients had associated TPA. The HS side made difference regarding the presence of TPA, with a left side prevalence (p=0.04, chi2 test). The anteromedial zone of temporal pole was affected in 27 (30%) out of 90 patients. In 63 (70%) patients the lateral zone were also affected. Patients with TPA were younger at seizure onset (p=0.018), but without association with duration of epilepsy. CONCLUSION: Our FLAIR study show temporal pole signal abnormality in 3/4 of patients with HS, mainly seen on the anteromedial region, with a larger prevalence when the left hippocampus was involved.

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