New cassane diterpenes from caesalpinia echinata

Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Química de Produtos Naturais. Belo Horizonte, MG, Brazil

Detalles Bibliográficos
Autores: Cota, Betania Barros, Oliveira, Djalma Menezes de, Siqueira Filho, Ezequias Pessoa de, Fagundes, Elaine Maria de Souza, Pimenta, Adriano M.c., Santos, Daniel M., Rabello, Ana Lucia Teles, Zani, Carlos Leomar
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Brasil
Institución:Fundação Oswaldo Cruz (FIOCRUZ)
Repositorio:Repositório Institucional da FIOCRUZ (ARCA)
Idioma:inglés
OAI Identifier:oai:arca.fiocruz.br:icict/8632
Acceso en línea:https://arca.fiocruz.br/handle/icict/8632
Access Level:acceso abierto
Palabra clave:Caesalpinia echinata
Leguminosae
Diterpene Cassane
Leishmania
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dc.title.none.fl_str_mv New cassane diterpenes from caesalpinia echinata
title New cassane diterpenes from caesalpinia echinata
spellingShingle New cassane diterpenes from caesalpinia echinata
Cota, Betania Barros
Caesalpinia echinata
Leguminosae
Diterpene Cassane
Leishmania
title_short New cassane diterpenes from caesalpinia echinata
title_full New cassane diterpenes from caesalpinia echinata
title_fullStr New cassane diterpenes from caesalpinia echinata
title_full_unstemmed New cassane diterpenes from caesalpinia echinata
title_sort New cassane diterpenes from caesalpinia echinata
dc.creator.none.fl_str_mv Cota, Betania Barros
Oliveira, Djalma Menezes de
Siqueira Filho, Ezequias Pessoa de
Fagundes, Elaine Maria de Souza
Pimenta, Adriano M.c.
Santos, Daniel M.
Rabello, Ana Lucia Teles
Zani, Carlos Leomar
author Cota, Betania Barros
author_facet Cota, Betania Barros
Oliveira, Djalma Menezes de
Siqueira Filho, Ezequias Pessoa de
Fagundes, Elaine Maria de Souza
Pimenta, Adriano M.c.
Santos, Daniel M.
Rabello, Ana Lucia Teles
Zani, Carlos Leomar
author_role author
author2 Oliveira, Djalma Menezes de
Siqueira Filho, Ezequias Pessoa de
Fagundes, Elaine Maria de Souza
Pimenta, Adriano M.c.
Santos, Daniel M.
Rabello, Ana Lucia Teles
Zani, Carlos Leomar
author2_role author
author
author
author
author
author
author
dc.subject.en.none.fl_str_mv Caesalpinia echinata
Leguminosae
Diterpene Cassane
Leishmania
topic Caesalpinia echinata
Leguminosae
Diterpene Cassane
Leishmania
description Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Química de Produtos Naturais. Belo Horizonte, MG, Brazil
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2014-10-20T14:44:28Z
dc.date.available.fl_str_mv 2014-10-20T14:44:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/8632
dc.identifier.issn.none.fl_str_mv 0367-326X
dc.identifier.doi.none.fl_str_mv 10.1016/j.fitote.2011.05.014
identifier_str_mv 0367-326X
10.1016/j.fitote.2011.05.014
url https://arca.fiocruz.br/handle/icict/8632
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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spelling 2014-10-20T14:44:28Z2014-10-20T14:44:28Z20110367-326Xhttps://arca.fiocruz.br/handle/icict/863210.1016/j.fitote.2011.05.014engElsevierNew cassane diterpenes from caesalpinia echinatainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Química de Produtos Naturais. Belo Horizonte, MG, BrazilUniversidade Estadual do Sudoeste de Bahia. Jequié, BA, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Química de Produtos Naturais. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Departamento de Fisiologia e Biofísica. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Departamento de Bioquímica e Imunologia. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Pesquisas Clínicas. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Química de Produtos Naturais. Belo Horizonte, MG, BrazilAn investigation of the ethanolic extract from stems of Caesalpinia echinata Lam Leguminosae-Caesalpinioideae) led to the isolation of five new cassane diterpenes along with known lambertianic acid. Their structures were determined based on spectroscopic methods. A preliminary study on leishmanicidal activity demonstrated that compounds 1, 2 and 6 were found to inhibit the growth of amastigote-like forms of Leishmania amazonensis without affecting mononuclear cells obtained from human peripheral blood.Caesalpinia echinataLeguminosaeDiterpene CassaneLeishmaniainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZCota, Betania BarrosOliveira, Djalma Menezes deSiqueira Filho, Ezequias Pessoa deFagundes, Elaine Maria de SouzaPimenta, Adriano M.c.Santos, Daniel M.Rabello, Ana Lucia TelesZani, Carlos LeomarLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://arca.fiocruz.br/bitstreams/619fe1a5-aa50-4bc8-92bb-0c2ee40b341c/download7d48279ffeed55da8dfe2f8e81f3b81fMD51falseAnonymousREADORIGINALNew cassane diterpenes from Caesalpinia echinata.pdfNew cassane diterpenes from Caesalpinia echinata.pdfapplication/pdf322346https://arca.fiocruz.br/bitstreams/9e1073c2-20f5-4f17-bc36-575becc78eb7/download005703ead6a099cb8967af34862ebd55MD52trueAnonymousREADTEXTNew cassane diterpenes from Caesalpinia echinata.pdf.txtNew cassane diterpenes from Caesalpinia echinata.pdf.txtExtracted texttext/plain30654https://arca.fiocruz.br/bitstreams/fb310046-b5ef-4732-82e5-f0708a155454/download66b408a79380ee1bfb81e721a98ae897MD57falseAnonymousREADTHUMBNAILNew cassane diterpenes from Caesalpinia echinata.pdf.jpgNew cassane diterpenes from Caesalpinia echinata.pdf.jpgGenerated Thumbnailimage/jpeg36742https://arca.fiocruz.br/bitstreams/4387eb4f-4b33-4099-bc53-f5c4a68f6451/download663971a4faf60f5b876549291819a039MD58falseAnonymousREADicict/86322025-12-10 14:01:56.522open.accessoai:arca.fiocruz.br:icict/8632https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-12-10T17:01:56Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)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