Endophytic fungus Phomopsis sp. as a source of 3-nitropropionic acid with larvicidal activity against Aedes aegypti (Linnaeus 1762, Diptera: Culicidae)

Background: Aedes aegypti is the primary vector of viruses, such as Zika, chikungunya, yellow fever, and dengue. In this context, a biomonitored chemical study was conducted to evaluate the activity of the crude extract of the endophytic fungus Phomopsis sp. against the larvae of Aedes aegypti. Meth...

ver descrição completa

Detalhes bibliográficos
Autores: Garcia, Armando da Costa, Júnior, Orivaldo Teixeira de Menezes, Mariano, Lissa Apolonia, Santiago, Letícia Corrêa, Araújo, Ângela Regina [UNESP], Monfardini, Julia Dietsche [UNESP], Simões, Rejane de Castro, de Oliveira, André Correa, Roque, Rosemary Aparecida, Tadei, Wanderli Pedro, Teles, Helder Lopes, de Oliveira, Camila Martins
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/249316
Acesso em linha:http://dx.doi.org/10.1590/0037-8682-0018-2022
http://hdl.handle.net/11449/249316
Access Level:acceso abierto
Palavra-chave:Biomonitored chemical
Dengue
Secondary metabolite
Descrição
Resumo:Background: Aedes aegypti is the primary vector of viruses, such as Zika, chikungunya, yellow fever, and dengue. In this context, a biomonitored chemical study was conducted to evaluate the activity of the crude extract of the endophytic fungus Phomopsis sp. against the larvae of Aedes aegypti. Methods: Crude extract, fractions, and isolated substances were evaluated in in-vitro assays against third-stage larvae of Aedes aegypti. Results: We isolated 3-nitropropionic acid with an LC50 of 15.172 ppm and LC90 of 18.178 ppm after 24 hours of larval exposure. Conclusions: The results indicated that 3-nitropropionic acid exerted larvicidal activity.

Registos relacionados