Pharmacognostic evaluation of Libidibia ferrea extracts and analysis of semi-solid dosage forms
A medicinal plant known as Jucá (Libidibia ferrea) is a Brazilian tree that possesses several therapeutic uses, including wound healing actions, due to the presence of polyphenols. Fruits from Libidibia ferrea var. leiostachya (Benth.) L.P. and Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz var. ferr...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2023 |
| País: | Brasil |
| Institución: | Fundação Oswaldo Cruz (FIOCRUZ) |
| Repositorio: | Revista Fitos |
| Idioma: | inglés |
| OAI Identifier: | oai:ojs.revistafitos.far.fiocruz.br:article/1492 |
| Acceso en línea: | https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1492 |
| Access Level: | acceso abierto |
| Palabra clave: | Libidibia ferrea Brazilian Ironwood Production of Herbal Medicines Quality control |
| Sumario: | A medicinal plant known as Jucá (Libidibia ferrea) is a Brazilian tree that possesses several therapeutic uses, including wound healing actions, due to the presence of polyphenols. Fruits from Libidibia ferrea var. leiostachya (Benth.) L.P. and Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz var. ferrea, were collected in Teresina (PI) and Jardinópolis (SP), respectively, and were used to prepare hydroethanolic and hydroglycolic extracts, produced in a 1:10 ratio. The extracts from the fruits from L. ferrea var. ferrea were used for the preparation of creams and ointments, containing 10 % (w/w) of these extracts. The extracts prepared with the fruits from L. ferrea var. ferrea (PI) are twice as concentrated in gallic acid content and in the percentage of dry residue, in comparison with those obtained from the fruits L. ferrea var. leiostachya. Among the formulations prepared, creams and ointments showed, statistically, the same concentration of total phenols, regardless of the type of extract used. The spreadability evaluation, which refers to the distribution of the pharmaceutical form by application area, showed that creams and ointments had very similar behaviors, except for the ointment produced with hydroglycolic extract, which was very fluid, making its therapeutic use unfeasible. |
|---|