Effect of the partially hydrogenated vegetable fat on the incorporation of trans fatty acids in rat tissues

The lipid composition of the diet can influence the profile of fatty acids the tissues. The objective of this study was to evaluate the incorporation of trans fatty acids in the liver and in the heart of rats. Two groups with twelve weanling Wistar rats each were fed two different diets for eight we...

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Detalles Bibliográficos
Autores: Maria SABARENSE, Céphora, MANCINI FILHO, Jorge
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Brasil
Institución:Pontifícia Universidade Católica de Campinas (PUC-CAMPINAS)
Repositorio:Revista de Nutrição
Idioma:portugués
OAI Identifier:oai:ojs.periodicos.puc-campinas.edu.br:article/9151
Acceso en línea:https://periodicos.puc-campinas.edu.br/nutricao/article/view/9151
Access Level:acceso abierto
Palabra clave:trans fatty acids
hydrogenated vegetable fat
essential fatty acids
long-chain
polyunsaturated fatty acids
rats
diet
ácidos graxos trans
gordura vegetal hidrogenada
ácidos graxos essenciais
ácidos graxos poliinsaturados
cadeia longa
ratos
dieta
Descripción
Sumario:The lipid composition of the diet can influence the profile of fatty acids the tissues. The objective of this study was to evaluate the incorporation of trans fatty acids in the liver and in the heart of rats. Two groups with twelve weanling Wistar rats each were fed two different diets for eight weeks. One of the diets (experimental) was rich in trans fatty acids (33.0% of total lipids) and presented minimal amounts of linoleic and a-linolenic acids (8.0% and 0.7%, respectively, of total lipids), while the other (control) was nutritionally adequate. The profile of fatty acids of the diets and tissues was evaluated by gas chromatography. There was an incorporation of 14.0% of the trans fatty acids in the liver and 8.6% in the heart. There was no inhibitory effect of the transfatty acids on the formation of arachidonic and docosahexaenoic acids in the liver. However, a significant decrease in the docosahexaenoic acid concentration was observed in the heart. It was probably a consequence of the deficiency of a-linolenic acid and of the incorporation of trans fatty acids.