Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes

An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synt...

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Detalhes bibliográficos
Autores: Mendez, Luciana, Mata, Ernesto Gabino
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/127696
Acesso em linha:http://hdl.handle.net/11336/127696
Access Level:acceso abierto
Palavra-chave:solid-phase synthesis
beta-lactam derivatives
staudinger cycloaddition
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
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spelling Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenesMendez, LucianaMata, Ernesto Gabinosolid-phase synthesisbeta-lactam derivativesstaudinger cycloadditionhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence.Fil: Mendez, Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaFil: Mata, Ernesto Gabino. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaAmerican Chemical Society2010-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/127696Mendez, Luciana; Mata, Ernesto Gabino; Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes; American Chemical Society; J. Comb. Chem.; 12; 6; 9-2010; 810-8131520-4766CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/cc100140rinfo:eu-repo/semantics/altIdentifier/doi/10.1021/cc100140rinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T13:50:23Zoai:ri.conicet.gov.ar:11336/127696instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 13:50:24.196CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
title Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
spellingShingle Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
Mendez, Luciana
solid-phase synthesis
beta-lactam derivatives
staudinger cycloaddition
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
title_short Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
title_full Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
title_fullStr Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
title_full_unstemmed Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
title_sort Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
dc.creator.none.fl_str_mv Mendez, Luciana
Mata, Ernesto Gabino
author Mendez, Luciana
author_facet Mendez, Luciana
Mata, Ernesto Gabino
author_role author
author2 Mata, Ernesto Gabino
author2_role author
dc.subject.none.fl_str_mv solid-phase synthesis
beta-lactam derivatives
staudinger cycloaddition
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
topic solid-phase synthesis
beta-lactam derivatives
staudinger cycloaddition
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
description An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence.
publishDate 2010
dc.date.none.fl_str_mv 2010-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/127696
Mendez, Luciana; Mata, Ernesto Gabino; Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes; American Chemical Society; J. Comb. Chem.; 12; 6; 9-2010; 810-813
1520-4766
CONICET Digital
CONICET
url http://hdl.handle.net/11336/127696
identifier_str_mv Mendez, Luciana; Mata, Ernesto Gabino; Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes; American Chemical Society; J. Comb. Chem.; 12; 6; 9-2010; 810-813
1520-4766
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/cc100140r
info:eu-repo/semantics/altIdentifier/doi/10.1021/cc100140r
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.228081

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