Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synt...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2010 |
| País: | Argentina |
| Institución: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/127696 |
| Acceso en línea: | http://hdl.handle.net/11336/127696 |
| Access Level: | acceso abierto |
| Palabra clave: | solid-phase synthesis beta-lactam derivatives staudinger cycloaddition https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Sumario: | An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence. |
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