15,21-Cyclowithanolides from Jaborosa bergii

Six new withanolides (1−6) were isolated from the aerial parts of Jaborosa bergii plants and characterized by spectroscopic methods (1D and 2D NMR, MS). Five of the new compounds presented a novel norbornane-type structure in ring D of the steroid nucleus (1−5), resulting from a carbon−carbon bond b...

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Detalles Bibliográficos
Autores: Nicotra, Viviana Estela, Gil, Roberto R., Vaccarini, Clarissa, Oberti, Juan Carlos María, Burton, Gerardo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2003
País:Argentina
Institución:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/41355
Acceso en línea:http://hdl.handle.net/11336/41355
Access Level:acceso abierto
Palabra clave:Withanolides
Monocotiledoneous Species
Dicotiledoneous Species
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
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repository_id_str
spelling 15,21-Cyclowithanolides from Jaborosa bergiiNicotra, Viviana EstelaGil, Roberto R.Vaccarini, ClarissaOberti, Juan Carlos MaríaBurton, GerardoWithanolidesMonocotiledoneous SpeciesDicotiledoneous Specieshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Six new withanolides (1−6) were isolated from the aerial parts of Jaborosa bergii plants and characterized by spectroscopic methods (1D and 2D NMR, MS). Five of the new compounds presented a novel norbornane-type structure in ring D of the steroid nucleus (1−5), resulting from a carbon−carbon bond between C-15 and C-21. The sixth withanolide isolated was the 5α-chloro-6β-hydroxy analogue (6) of 2,3-dehydrojaborosalactol M (7), previously isolated from this plant. Compound 1 showed selective phytotoxicity toward monocotiledoneous and dicotiledoneous species.Fil: Nicotra, Viviana Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Gil, Roberto R.. Carnegie Mellon University; Estados UnidosFil: Vaccarini, Clarissa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Oberti, Juan Carlos María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Burton, Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Unidad de Microanálisis y Métodos Físicos en Química Orgánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Unidad de Microanálisis y Métodos Físicos en Química Orgánica; ArgentinaAmerican Chemical Society2003-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/41355Nicotra, Viviana Estela; Gil, Roberto R.; Vaccarini, Clarissa; Oberti, Juan Carlos María; Burton, Gerardo; 15,21-Cyclowithanolides from Jaborosa bergii; American Chemical Society; Journal of Natural Products; 66; 11; 6-2003; 1471-14750163-38641520-6025CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pubmed/14640521info:eu-repo/semantics/altIdentifier/doi/10.1021/np030248cinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2024-05-08T14:07:18Zoai:ri.conicet.gov.ar:11336/41355instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982024-05-08 14:07:18.788CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv 15,21-Cyclowithanolides from Jaborosa bergii
title 15,21-Cyclowithanolides from Jaborosa bergii
spellingShingle 15,21-Cyclowithanolides from Jaborosa bergii
Nicotra, Viviana Estela
Withanolides
Monocotiledoneous Species
Dicotiledoneous Species
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
title_short 15,21-Cyclowithanolides from Jaborosa bergii
title_full 15,21-Cyclowithanolides from Jaborosa bergii
title_fullStr 15,21-Cyclowithanolides from Jaborosa bergii
title_full_unstemmed 15,21-Cyclowithanolides from Jaborosa bergii
title_sort 15,21-Cyclowithanolides from Jaborosa bergii
dc.creator.none.fl_str_mv Nicotra, Viviana Estela
Gil, Roberto R.
Vaccarini, Clarissa
Oberti, Juan Carlos María
Burton, Gerardo
author Nicotra, Viviana Estela
author_facet Nicotra, Viviana Estela
Gil, Roberto R.
Vaccarini, Clarissa
Oberti, Juan Carlos María
Burton, Gerardo
author_role author
author2 Gil, Roberto R.
Vaccarini, Clarissa
Oberti, Juan Carlos María
Burton, Gerardo
author2_role author
author
author
author
dc.subject.none.fl_str_mv Withanolides
Monocotiledoneous Species
Dicotiledoneous Species
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
topic Withanolides
Monocotiledoneous Species
Dicotiledoneous Species
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
description Six new withanolides (1−6) were isolated from the aerial parts of Jaborosa bergii plants and characterized by spectroscopic methods (1D and 2D NMR, MS). Five of the new compounds presented a novel norbornane-type structure in ring D of the steroid nucleus (1−5), resulting from a carbon−carbon bond between C-15 and C-21. The sixth withanolide isolated was the 5α-chloro-6β-hydroxy analogue (6) of 2,3-dehydrojaborosalactol M (7), previously isolated from this plant. Compound 1 showed selective phytotoxicity toward monocotiledoneous and dicotiledoneous species.
publishDate 2003
dc.date.none.fl_str_mv 2003-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/41355
Nicotra, Viviana Estela; Gil, Roberto R.; Vaccarini, Clarissa; Oberti, Juan Carlos María; Burton, Gerardo; 15,21-Cyclowithanolides from Jaborosa bergii; American Chemical Society; Journal of Natural Products; 66; 11; 6-2003; 1471-1475
0163-3864
1520-6025
CONICET Digital
CONICET
url http://hdl.handle.net/11336/41355
identifier_str_mv Nicotra, Viviana Estela; Gil, Roberto R.; Vaccarini, Clarissa; Oberti, Juan Carlos María; Burton, Gerardo; 15,21-Cyclowithanolides from Jaborosa bergii; American Chemical Society; Journal of Natural Products; 66; 11; 6-2003; 1471-1475
0163-3864
1520-6025
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pubmed/14640521
info:eu-repo/semantics/altIdentifier/doi/10.1021/np030248c
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 15.223283

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