15,21-Cyclowithanolides from Jaborosa bergii
Six new withanolides (1−6) were isolated from the aerial parts of Jaborosa bergii plants and characterized by spectroscopic methods (1D and 2D NMR, MS). Five of the new compounds presented a novel norbornane-type structure in ring D of the steroid nucleus (1−5), resulting from a carbon−carbon bond b...
| Autores: | , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2003 |
| País: | Argentina |
| Recursos: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/41355 |
| Acesso em linha: | http://hdl.handle.net/11336/41355 |
| Access Level: | acceso abierto |
| Palavra-chave: | Withanolides Monocotiledoneous Species Dicotiledoneous Species https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Resumo: | Six new withanolides (1−6) were isolated from the aerial parts of Jaborosa bergii plants and characterized by spectroscopic methods (1D and 2D NMR, MS). Five of the new compounds presented a novel norbornane-type structure in ring D of the steroid nucleus (1−5), resulting from a carbon−carbon bond between C-15 and C-21. The sixth withanolide isolated was the 5α-chloro-6β-hydroxy analogue (6) of 2,3-dehydrojaborosalactol M (7), previously isolated from this plant. Compound 1 showed selective phytotoxicity toward monocotiledoneous and dicotiledoneous species. |
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