Solid-supported cross-metathesis and a formal alkane metathesis for the generation of biologically relevant molecules
Solid-phase synthetic strategies towards the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium catalyzed cross-metathesis and reduction...
| Autores: | , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | Argentina |
| Recursos: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repositorio: | CONICET Digital (CONICET) |
| Idioma: | inglés |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/6067 |
| Acesso em linha: | http://hdl.handle.net/11336/6067 |
| Access Level: | acceso abierto |
| Palavra-chave: | Olefin Metathesis Solid-Phase Organic Synthesis Chalcones Microwave Heating https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Resumo: | Solid-phase synthetic strategies towards the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages |
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