Solid-supported cross-metathesis and a formal alkane metathesis for the generation of biologically relevant molecules
Solid-phase synthetic strategies towards the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium catalyzed cross-metathesis and reduction...
| Authors: | , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2015 |
| Country: | Argentina |
| Institution: | Consejo Nacional de Investigaciones Científicas y Técnicas |
| Repository: | CONICET Digital (CONICET) |
| Language: | English |
| OAI Identifier: | oai:ri.conicet.gov.ar:11336/6067 |
| Online Access: | http://hdl.handle.net/11336/6067 |
| Access Level: | Open access |
| Keyword: | Olefin Metathesis Solid-Phase Organic Synthesis Chalcones Microwave Heating https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
| Summary: | Solid-phase synthetic strategies towards the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages |
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