Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents
Objective: To determine the ultrasonography and liver functional alterations in obese children and adolescents. Methods: non-experimental, analytical, cross-sectional study carried out in children and adolescents with obesity from five to seventeen years of age. The sample was divided into two group...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | México |
| Institución: | UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO |
| Repositorio: | Atención Familiar |
| Idioma: | español |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/78795 |
| Acceso en línea: | https://www.revistas.unam.mx/index.php/atencion_familiar/article/view/78795 |
| Access Level: | acceso abierto |
| Palabra clave: | obesidad niños adolescentes resistencia a la insulina enfermedad del hígado graso no alcohólico hepatomegalia hígado graso prueba de función hepática Obesity Children Adolescent Insulin Resistance Nonalcoholic Fatty Liver Disease Hepatomegaly Fatty Liver Liver Function Tests |
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Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents Alteraciones ultrasonográficas y funcionales hepáticas en niños y adolescentes con obesidad |
| title |
Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents |
| spellingShingle |
Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents González Pérez, Brian obesidad niños adolescentes resistencia a la insulina enfermedad del hígado graso no alcohólico hepatomegalia hígado graso prueba de función hepática Obesity Children Adolescent Insulin Resistance Nonalcoholic Fatty Liver Disease Hepatomegaly Fatty Liver Liver Function Tests |
| title_short |
Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents |
| title_full |
Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents |
| title_fullStr |
Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents |
| title_full_unstemmed |
Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents |
| title_sort |
Ultrasonography and Functional Hepatic Alterations in Obese Children and Adolescents |
| dc.creator.none.fl_str_mv |
González Pérez, Brian Salas Flores, Ricardo Yáñez Casados, Brisia Minerva Hernández Carranco, Roandy Gaspar Reséndiz González, Eunice Áspera Campos, Teresa |
| author |
González Pérez, Brian |
| author_facet |
González Pérez, Brian Salas Flores, Ricardo Yáñez Casados, Brisia Minerva Hernández Carranco, Roandy Gaspar Reséndiz González, Eunice Áspera Campos, Teresa |
| author_role |
author |
| author2 |
Salas Flores, Ricardo Yáñez Casados, Brisia Minerva Hernández Carranco, Roandy Gaspar Reséndiz González, Eunice Áspera Campos, Teresa |
| author2_role |
author author author author author |
| dc.subject.none.fl_str_mv |
obesidad niños adolescentes resistencia a la insulina enfermedad del hígado graso no alcohólico hepatomegalia hígado graso prueba de función hepática Obesity Children Adolescent Insulin Resistance Nonalcoholic Fatty Liver Disease Hepatomegaly Fatty Liver Liver Function Tests |
| topic |
obesidad niños adolescentes resistencia a la insulina enfermedad del hígado graso no alcohólico hepatomegalia hígado graso prueba de función hepática Obesity Children Adolescent Insulin Resistance Nonalcoholic Fatty Liver Disease Hepatomegaly Fatty Liver Liver Function Tests |
| description |
Objective: To determine the ultrasonography and liver functional alterations in obese children and adolescents. Methods: non-experimental, analytical, cross-sectional study carried out in children and adolescents with obesity from five to seventeen years of age. The sample was divided into two groups, one with the presence of non-alcoholic fatty liver disease (nafld) (group 1) and the other with normal liver (group 2), determined by ultrasonography. Anthropometry, body composition and serum level measurements were performed to establish a biochemical and functional liver profile. Differences between groups were analyzed by Student’s t-test, p<0.05. Results: a total of 59 participants were studied, of which 54.2% (n=32) were female and 45.8% (n=27) male. The average age of the population studied was 10.05 ± 2.5 years. Group 1 consisted of a total of 72.9% of patients (n=43), and group 2 consisted of 27.1% (n=16). The findings showed alterations in serum levels, biochemical profile and liver functionality. Fasting transaminases and insulin were significantly higher in group 1 patients than in group 2 (p<0.05). A higher insulin resistance (p=0.000) was also observed in group 1. Conclusions: there were alterations in serum levels, biochemical profile and hepatic functionality. Ultrasound and liver function tests should be part of the initial evaluation for early identification of this pathology in obese infants. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-03-23 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://www.revistas.unam.mx/index.php/atencion_familiar/article/view/78795 10.22201/fm.14058871p.2021.2.78795 |
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https://www.revistas.unam.mx/index.php/atencion_familiar/article/view/78795 |
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10.22201/fm.14058871p.2021.2.78795 |
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spa |
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spa |
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https://www.revistas.unam.mx/index.php/atencion_familiar/article/view/78795/69867 |
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Derechos de autor 2021 Universidad Nacional Autónoma de México info:eu-repo/semantics/openAccess |
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Derechos de autor 2021 Universidad Nacional Autónoma de México |
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openAccess |
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application/pdf |
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Facultad de Medicina |
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Facultad de Medicina |
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Atención Familiar; Vol. 28 Núm. 2; 82-88 2992-782X 10.22201/fm.14058871p.2021.2 reponame:Atención Familiar instname:UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO instacron:UNAM |
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UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO |
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UNAM |
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UNAM |
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Atención Familiar |
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Atención Familiar |
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Ultrasonography and Functional Hepatic Alterations in Obese Children and AdolescentsAlteraciones ultrasonográficas y funcionales hepáticas en niños y adolescentes con obesidadGonzález Pérez, BrianSalas Flores, RicardoYáñez Casados, Brisia MinervaHernández Carranco, Roandy GasparReséndiz González, EuniceÁspera Campos, Teresaobesidadniñosadolescentesresistencia a la insulinaenfermedad del hígado graso no alcohólicohepatomegaliahígado grasoprueba de función hepáticaObesityChildrenAdolescentInsulin ResistanceNonalcoholic Fatty Liver DiseaseHepatomegalyFatty LiverLiver Function TestsObjective: To determine the ultrasonography and liver functional alterations in obese children and adolescents. Methods: non-experimental, analytical, cross-sectional study carried out in children and adolescents with obesity from five to seventeen years of age. The sample was divided into two groups, one with the presence of non-alcoholic fatty liver disease (nafld) (group 1) and the other with normal liver (group 2), determined by ultrasonography. Anthropometry, body composition and serum level measurements were performed to establish a biochemical and functional liver profile. Differences between groups were analyzed by Student’s t-test, p<0.05. Results: a total of 59 participants were studied, of which 54.2% (n=32) were female and 45.8% (n=27) male. The average age of the population studied was 10.05 ± 2.5 years. Group 1 consisted of a total of 72.9% of patients (n=43), and group 2 consisted of 27.1% (n=16). The findings showed alterations in serum levels, biochemical profile and liver functionality. Fasting transaminases and insulin were significantly higher in group 1 patients than in group 2 (p<0.05). A higher insulin resistance (p=0.000) was also observed in group 1. Conclusions: there were alterations in serum levels, biochemical profile and hepatic functionality. Ultrasound and liver function tests should be part of the initial evaluation for early identification of this pathology in obese infants.Objetivo: determinar las alteraciones ultrasonográficas y funcionales hepáticas en niños y adolescentes con obesidad. Métodos: se realizó un estudio no experimental, analítico, de corte transversal en niños y adolescentes de cinco a diecisiete años con obesidad. La muestra se separó en dos grupos, uno con la presencia de enfermedad de hígado graso no alcohólico (grupo 1) y el otro con hígado normal (grupo 2), determinado mediante ultrasonografía. Se realizó antropometría, composición corporal y mediciones de niveles séricos para establecer un perfil bioquímico y funcional hepático. Las diferencias entre grupos se analizaron mediante la prueba t de Student, p<0.05. Resultados: se estudiaron un total de 59 participantes de los cuales 54.2% (n=32) fue de sexo femenino y 45.8% (n=27), masculino. La edad promedio de la población estudiada fue de 10.05 ± 2.5 años. El grupo 1 estuvo constituido por un total de 72.9% de pacientes (n=43), y el grupo 2 por 27.1% (n=16). Los hallazgos mostraron alteraciones en los niveles séricos, perfil bioquímico y funcionalidad hepática. Las transaminasas e insulina en ayuno fueron significativamente más elevados en los pacientes del grupo 1 que en los del grupo 2 (p<0.05). También se observó mayor resistencia a la insulina (p=0.000) en el grupo 1. Conclusiones: existieron alteraciones en los niveles séricos, perfil bioquímico y funcionalidad hepática. El ultrasonido y las pruebas de funcionamiento hepático deben formar parte de la valoración inicial para la identificación temprana de esta patología en infantes con obesidad. Facultad de Medicina2021-03-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.unam.mx/index.php/atencion_familiar/article/view/7879510.22201/fm.14058871p.2021.2.78795Atención Familiar; Vol. 28 Núm. 2; 82-882992-782X10.22201/fm.14058871p.2021.2reponame:Atención Familiarinstname:UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICOinstacron:UNAMspahttps://www.revistas.unam.mx/index.php/atencion_familiar/article/view/78795/69867Derechos de autor 2021 Universidad Nacional Autónoma de Méxicoinfo:eu-repo/semantics/openAccessoai:ojs.pkp.sfu.ca:article/787952024-08-16T16:51:47Z |
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