Natural Deep Eutectic Solvents as Performance Additivesfor Peroxygenase Catalysis

[EN] Natural deep eutectic solvents (NADES) are proposed as alternative solvents for peroxygenase-catalysed oxyfunctionali-zation reactions. Choline chloride-based NADES are of particularinterest as they can serve as solvent, enzyme-stabiliser and sacrificial electron donor for the in situ H2O2gener...

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Detalhes bibliográficos
Autores: Ma, Yanhang, Li, Yongru, Ali, Shahid, Li, Peilin, Zhang, Wuyuan, Rauch, Marine C. R., Willot, Sébastien J.-P., Ribitsch, Doris, Choi, Young Hae, Alcalde Galeote, Miguel, Hollmann, Frank, Wang, Yonghua
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/215072
Acesso em linha:http://hdl.handle.net/10261/215072
Access Level:Acceso aberto
Palavra-chave:Peroxygenases
Deep eutectic solvents
Cholineoxidase
Oxyfunctionalisation reactions
Descrição
Resumo:[EN] Natural deep eutectic solvents (NADES) are proposed as alternative solvents for peroxygenase-catalysed oxyfunctionali-zation reactions. Choline chloride-based NADES are of particularinterest as they can serve as solvent, enzyme-stabiliser and sacrificial electron donor for the in situ H2O2generation. This report provides the first proof-of-concept and basic character-isation of this new reaction system. Highly promising turnovernumbers for the biocatalysts of up to 200,000 have been achieved.

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