Long-term cost-effectiveness analysis of sacral neuromodulation in the treatment of severe faecal incontinence

Aim: The aim of this study was to evaluate the long-term cost-effectiveness of sacralneuromodulation in the treatment of severe faecal incontinence as compared with symp-tomatic management.Methods: In the public health field, a micro-costing evaluation method was conductedfrom the perspectives of th...

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Detalles Bibliográficos
Autores: Miguel Valencia, Mario Javier de, Cabasés Hita, Juan Manuel, Sánchez Iriso, Eduardo, Oteiza Martínez, Fabiola Irache, Alberdi Ibáñez, Iñaki, Álvarez López, Alfonso, Ortiz Hurtado, Héctor, Miguel Velasco, Mario de
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2023
País:España
Institución:Universidad Pública de Navarra
Repositorio:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
OAI Identifier:oai:academica-e.unavarra.es:2454/56105
Acceso en línea:https://hdl.handle.net/2454/56105
Access Level:acceso abierto
Palabra clave:Cost-effectiveness
Faecal incontinence
Long-term
Sacral neuromodulation
Descripción
Sumario:Aim: The aim of this study was to evaluate the long-term cost-effectiveness of sacralneuromodulation in the treatment of severe faecal incontinence as compared with symp-tomatic management.Methods: In the public health field, a micro-costing evaluation method was conductedfrom the perspectives of the health system and the society. The incremental cost-effectiveness ratio was used as a decision index, and we considered various scenariosto evaluate the impact of the cost of symptomatic management and percutaneous nerveevaluation success rate in its calculation. Clinical data were retrieved from a consecutivecohort of 93 patients with severe faecal incontinence undergoing sacral neuromodula-tion after a failure of conservative (pharmacological and biofeedback) and/or surgical(sphincteroplasty) first-line treatments were considered.Results: The long-term incremental cost-effectiveness ratio comparing sacral neuromod-ulation versus symptomatic management was 14347€/QALY and 28523€/QALY from thesocietal and health service provider's perspectives, respectively. If the definitive pulsegenerator implant success rate was 100%, incremental cost-effectiveness would corre-spond to 6831€/QALY and 16761€/QALY, respectively.Conclusions: Sacral neuromodulation may be considered a cost-effective technique inthe long-term treatment of severe faecal incontinence from the societal and health caresector perspectives. Improving patient selection and determining the predictive outcomefactors for successful sacral neuromodulation in the treatment of faecal incontinencewould improve cost-effectiveness.