Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)

In this study, the protective effects of diphenyl diselenide [(PhSe)2] on quinclorac- induced toxicity were investigated in silver catfish (Rhamdia quelen). The fish were fed for 60 days with a diet in the absence or in the presence of 3.0 mg/Kg (PhSe)2. Animals were further exposed to 1 mg/L quincl...

ver descrição completa

Detalhes bibliográficos
Autores: Menezes, Charlene C., Ruiz-Jarabo, Ignacio, Martos-Sitcha, Juan Antonio, Baldisserotto, Bernardo, Mancera, Juan Miguel, Rosemberg, Denis Broock, Loro, Vania Lucía
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/168445
Acesso em linha:http://hdl.handle.net/10261/168445
Access Level:acceso abierto
id ES_e7cf7f0414cbe8a05f643b66ddc176d4
oai_identifier_str oai:digital.csic.es:10261/168445
network_acronym_str ES
network_name_str España
repository_id_str
spelling Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)Menezes, Charlene C.Ruiz-Jarabo, IgnacioMartos-Sitcha, Juan AntonioBaldisserotto, BernardoMancera, Juan MiguelRosemberg, Denis BroockLoro, Vania LucíaIn this study, the protective effects of diphenyl diselenide [(PhSe)2] on quinclorac- induced toxicity were investigated in silver catfish (Rhamdia quelen). The fish were fed for 60 days with a diet in the absence or in the presence of 3.0 mg/Kg (PhSe)2. Animals were further exposed to 1 mg/L quinclorac for 8 days. At the end of experimental period, fish were euthanized and biopsies from liver and gills, as well as blood samples, were collected. The cortisol and metabolic parameters were determined in plasma, and those enzyme activities related to osmoregulation were assayed in the gills. In liver, some important enzyme activities of the intermediary metabolism and oxidative stress-related parameters, such as thiobarbituric acid-reactive substance (TBARS), protein carbonyl, catalase (CAT), superoxide dismutase (SOD), glutathione S-transferase (GST), nonprotein thiols (NPSH) and ascorbic acid contents were also evaluated. Compared to the control group, quinclorac exposure significantly decreased hepatosomatic index and increased cortisol and lactate values in plasma. Moreover, the activities of fructose biphosphatase (FBPase), glucose-6-phosphate dehydrogenase (G6Pase), glycogen phosphorilase (GPase) and aspartate aminotransferase (AST) were significantly increased in liver. Quinclorac also induced lipid peroxidation while the activity of SOD, NPSH and ascorbic acid levels decreased in the liver. However, dietary (PhSe)2 reduced the herbicide-induced effects on the studied parameters. In conclusion, (PhSe)2 has beneficial properties based on its ability to attenuate toxicity induced by quinclorac by regulating energy metabolism and oxidative stress-related parameters.This study was supported by CAPES (Ministry of Education of Brazil, Brazil) through the program PNPD-CAPES (Programa Nacional de PÃ3s-Doutorado) to the student CM; CNPq research fellowship to VLL and BB; and by the project AGL2010-14876 (Ministry of Science and Innovation, Spain) to JMM.Peer reviewedPublic Library of ScienceCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil)Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil)Ministerio de Ciencia e Innovación (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201820182014info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/168445reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1371/journal.pone.0114233Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1684452026-05-22T06:33:51Z
dc.title.none.fl_str_mv Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
title Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
spellingShingle Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
Menezes, Charlene C.
title_short Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
title_full Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
title_fullStr Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
title_full_unstemmed Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
title_sort Diet with Diphenyl Diselenide Mitigates Quinclorac Toxicity in Silver Catfish (Rhamdia quelen)
dc.creator.none.fl_str_mv Menezes, Charlene C.
Ruiz-Jarabo, Ignacio
Martos-Sitcha, Juan Antonio
Baldisserotto, Bernardo
Mancera, Juan Miguel
Rosemberg, Denis Broock
Loro, Vania Lucía
author Menezes, Charlene C.
author_facet Menezes, Charlene C.
Ruiz-Jarabo, Ignacio
Martos-Sitcha, Juan Antonio
Baldisserotto, Bernardo
Mancera, Juan Miguel
Rosemberg, Denis Broock
Loro, Vania Lucía
author_role author
author2 Ruiz-Jarabo, Ignacio
Martos-Sitcha, Juan Antonio
Baldisserotto, Bernardo
Mancera, Juan Miguel
Rosemberg, Denis Broock
Loro, Vania Lucía
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil)
Ministerio de Ciencia e Innovación (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
description In this study, the protective effects of diphenyl diselenide [(PhSe)2] on quinclorac- induced toxicity were investigated in silver catfish (Rhamdia quelen). The fish were fed for 60 days with a diet in the absence or in the presence of 3.0 mg/Kg (PhSe)2. Animals were further exposed to 1 mg/L quinclorac for 8 days. At the end of experimental period, fish were euthanized and biopsies from liver and gills, as well as blood samples, were collected. The cortisol and metabolic parameters were determined in plasma, and those enzyme activities related to osmoregulation were assayed in the gills. In liver, some important enzyme activities of the intermediary metabolism and oxidative stress-related parameters, such as thiobarbituric acid-reactive substance (TBARS), protein carbonyl, catalase (CAT), superoxide dismutase (SOD), glutathione S-transferase (GST), nonprotein thiols (NPSH) and ascorbic acid contents were also evaluated. Compared to the control group, quinclorac exposure significantly decreased hepatosomatic index and increased cortisol and lactate values in plasma. Moreover, the activities of fructose biphosphatase (FBPase), glucose-6-phosphate dehydrogenase (G6Pase), glycogen phosphorilase (GPase) and aspartate aminotransferase (AST) were significantly increased in liver. Quinclorac also induced lipid peroxidation while the activity of SOD, NPSH and ascorbic acid levels decreased in the liver. However, dietary (PhSe)2 reduced the herbicide-induced effects on the studied parameters. In conclusion, (PhSe)2 has beneficial properties based on its ability to attenuate toxicity induced by quinclorac by regulating energy metabolism and oxidative stress-related parameters.
publishDate 2014
dc.date.none.fl_str_mv 2014
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/168445
url http://hdl.handle.net/10261/168445
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1371/journal.pone.0114233
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869422887168901120
score 15,812455

Registos relacionados