Comparing the Proteomic Profiles of Extracellular Vesicles Isolated using Different Methods from Long-term Stored Plasma Samples

The lack of standardized protocols for isolating extracellular vesicles (EVs), especially from biobank-stored blood plasma, translates to limitations for the study of new biomarkers. This study examines whether a combination of current isolation methods could enhance the specificity and purity of is...

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Detalles Bibliográficos
Autores: Torres, Ana, Bernardo, Lorena, Sánchez, Carmen, Morato, Esperanza, Solana, José Carlos, Carrillo, Eugenia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/366548
Acceso en línea:http://hdl.handle.net/10261/366548
Access Level:acceso abierto
Palabra clave:Extracellular Vesicles
Plasma
Proteomics
Size Exclusion Chromatography
Ultracentrifugation.
Descripción
Sumario:The lack of standardized protocols for isolating extracellular vesicles (EVs), especially from biobank-stored blood plasma, translates to limitations for the study of new biomarkers. This study examines whether a combination of current isolation methods could enhance the specificity and purity of isolated EVs for diagnosis and personalized medicine purposes.