Reactivity and Applications of Singlet Oxygen Molecule

Reactive oxygen species (ROS) are molecules produced in living organisms, in the environment, and in various chemical reactions. The main species include, among others, singlet oxygen (1O2), the superoxide anion radical (•O2 ), the hydroxyl radical (HO•), and the hydroperoxyl radical (HOO•). In gene...

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Detalhes bibliográficos
Autores: Curieses Andrés, Celia María, Pérez de la Lastra, José Manuel, Andrés Juan, Celia, Plou Gasca, Francisco José, Pérez-Lebeña, Eduardo
Formato: otro
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/348786
Acesso em linha:http://hdl.handle.net/10261/348786
Access Level:acceso abierto
Palavra-chave:singlet oxygen
photochemistry
phototherapy
photosensitizers
singlet oxygen generation methods
molecules
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spelling Reactivity and Applications of Singlet Oxygen MoleculeCurieses Andrés, Celia MaríaPérez de la Lastra, José ManuelAndrés Juan, CeliaPlou Gasca, Francisco JoséPérez-Lebeña, Eduardosinglet oxygenphotochemistryphototherapyphotosensitizerssinglet oxygen generation methodsmoleculesReactive oxygen species (ROS) are molecules produced in living organisms, in the environment, and in various chemical reactions. The main species include, among others, singlet oxygen (1O2), the superoxide anion radical (•O2 ), the hydroxyl radical (HO•), and the hydroperoxyl radical (HOO•). In general, the reactivity of 1O2 is lower than that of HO• but even higher than that of •O2 . Singlet oxygen is the lowest energy excited state of molecular oxygen, but it is also a highly reactive species, which can initiate oxidation reactions of biomolecules such as amino acids, proteins, nucleic acids, and lipids, either by a direct reaction or by the induction of ROS. Singlet oxygen is a highly reactive electrophilic species that reacts with electron-rich molecules and is related to several types of pathologies. To inhibit the oxidation of biomolecules with this species, some substances act as antioxidants by performing a quenching effect. In this chapter, aspects such as its physicochemical properties, methods of generation and detection, as well as the reactivity of this molecule are detailed.This research was funded by Agencia Canaria de Investigación, Innovación y Sociedad de la Información (ACIISI) del Gobierno de Canarias, Project ProID2020010134, Caja Canarias, Project 2019SP43, the Spanish Ministry of Economy and Competitiveness (Grant PID2019-105838RB-C31) and the State Plan for Scientific, Technical Research and Innovation 2021–2023 from the Spanish Ministry of Science and Innovation (project PLEC2022-009507) and the State Plan for Scientific, Technical Research and Innovation 2021–2023 from the Spanish Ministry of Science and Innovation (project PLEC2022-009507).Peer reviewedInTechOpenAgencia Canaria de Investigación, Innovación y Sociedad de la InformaciónCaja CanariasMinisterio de Economía y Competitividad (España)Ministerio de Ciencia e Innovación (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242023info:eu-repo/semantics/otherhttp://purl.org/coar/resource_type/c_3248Publisher's versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookParthttp://hdl.handle.net/10261/348786reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-105838RB-C31info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PLEC2022-009507http://dx.doi.org/10.5772/intechopen.112024Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3487862026-05-22T06:33:51Z
dc.title.none.fl_str_mv Reactivity and Applications of Singlet Oxygen Molecule
title Reactivity and Applications of Singlet Oxygen Molecule
spellingShingle Reactivity and Applications of Singlet Oxygen Molecule
Curieses Andrés, Celia María
singlet oxygen
photochemistry
phototherapy
photosensitizers
singlet oxygen generation methods
molecules
title_short Reactivity and Applications of Singlet Oxygen Molecule
title_full Reactivity and Applications of Singlet Oxygen Molecule
title_fullStr Reactivity and Applications of Singlet Oxygen Molecule
title_full_unstemmed Reactivity and Applications of Singlet Oxygen Molecule
title_sort Reactivity and Applications of Singlet Oxygen Molecule
dc.creator.none.fl_str_mv Curieses Andrés, Celia María
Pérez de la Lastra, José Manuel
Andrés Juan, Celia
Plou Gasca, Francisco José
Pérez-Lebeña, Eduardo
author Curieses Andrés, Celia María
author_facet Curieses Andrés, Celia María
Pérez de la Lastra, José Manuel
Andrés Juan, Celia
Plou Gasca, Francisco José
Pérez-Lebeña, Eduardo
author_role author
author2 Pérez de la Lastra, José Manuel
Andrés Juan, Celia
Plou Gasca, Francisco José
Pérez-Lebeña, Eduardo
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Agencia Canaria de Investigación, Innovación y Sociedad de la Información
Caja Canarias
Ministerio de Economía y Competitividad (España)
Ministerio de Ciencia e Innovación (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv singlet oxygen
photochemistry
phototherapy
photosensitizers
singlet oxygen generation methods
molecules
topic singlet oxygen
photochemistry
phototherapy
photosensitizers
singlet oxygen generation methods
molecules
description Reactive oxygen species (ROS) are molecules produced in living organisms, in the environment, and in various chemical reactions. The main species include, among others, singlet oxygen (1O2), the superoxide anion radical (•O2 ), the hydroxyl radical (HO•), and the hydroperoxyl radical (HOO•). In general, the reactivity of 1O2 is lower than that of HO• but even higher than that of •O2 . Singlet oxygen is the lowest energy excited state of molecular oxygen, but it is also a highly reactive species, which can initiate oxidation reactions of biomolecules such as amino acids, proteins, nucleic acids, and lipids, either by a direct reaction or by the induction of ROS. Singlet oxygen is a highly reactive electrophilic species that reacts with electron-rich molecules and is related to several types of pathologies. To inhibit the oxidation of biomolecules with this species, some substances act as antioxidants by performing a quenching effect. In this chapter, aspects such as its physicochemical properties, methods of generation and detection, as well as the reactivity of this molecule are detailed.
publishDate 2023
dc.date.none.fl_str_mv 2023
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/other
http://purl.org/coar/resource_type/c_3248
Publisher's version
info:eu-repo/semantics/publishedVersion
dc.type.openaire.fl_str_mv info:eu-repo/semantics/bookPart
format other
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/348786
url http://hdl.handle.net/10261/348786
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-105838RB-C31
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PLEC2022-009507
http://dx.doi.org/10.5772/intechopen.112024
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv InTechOpen
publisher.none.fl_str_mv InTechOpen
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
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repository.name.fl_str_mv
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