From diverse CT scans to generalization: towards robust abdominal organ segmentation

Abdominal organ segmentation is a rapidly advancing area in medical imaging, boasting numerous remarkable applications in clinical and research settings. Despite these advancements, most existing segmentation models are developed using single-source data. This homogeneity raises concerns regarding t...

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Detalles Bibliográficos
Autor: Álvarez Llopis, Nicolás
Tipo de recurso: tesis de maestría
Fecha de publicación:2024
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/413967
Acceso en línea:https://hdl.handle.net/2117/413967
Access Level:acceso abierto
Palabra clave:Tomography
Image segmentation
Segmentació d'òrgans
Tomografia computada
Generalizabilitat
CNN
ViT
nnUNet
Swin-UNETR
Organ Segmentation
Computed Tomography
Generalizability
Tomografia
Imatges--Segmentació
Àrees temàtiques de la UPC::Informàtica::Infografia
Descripción
Sumario:Abdominal organ segmentation is a rapidly advancing area in medical imaging, boasting numerous remarkable applications in clinical and research settings. Despite these advancements, most existing segmentation models are developed using single-source data. This homogeneity raises concerns regarding the applicability of these models to more diverse and complex clinical scenarios. This study aimed to develop a generalizable model for the semantic segmentation of abdominal organs using three widely recognized public datasets: BTCV, AMOS, and TotalSegmentator. Extensive cleaning and preprocessing were undertaken to address the challenges posed by data heterogeneity. The merging process resulted in a diverse and comprehensive dataset of 680 CT scans that encapsulates varied image conditions and anatomical representations. The comparative analysis utilized two architectural frameworks: nnUNet, representing Convolutional Neural Networks, and Swin-UNETR embodying Vision Transformers. Results demonstrate the superiority of the nnUNet model across all experiments, demonstrating superior robustness and adaptability under diverse conditions and unseen cases, although further research could contribute to achieving a more balanced performance across patient groups. With an average Dice Similarity Coefficient of 92.3%, the developed nnUNet model establishes itself as a highly effective and competitive approach in the field of abdominal organ segmentation.