Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients

Objectives/Hypothesis Our objective was to determine whether drug-induced sleep apnea (DISE) affects the successfulness of the surgical outcome. Study Design Prospective, seven-country, nonrandomized trial. Methods There were 326 consecutive obstructive sleep apnea (OSA) patients who had nose, palat...

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Autores: Pang KP, Baptista PM, Olszewska E, Braverman I, Carrasco-Llatas, Marina, Kishore S, Chandra S, Yang HC, Wang CMZ, Chan YH, Pang KA, Pang EB, Rotenberg B
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2020
País:España
Recursos:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositório:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p3496
Acesso em linha:https://fisabio.portalinvestigacion.com/publicaciones/3496
Access Level:Acceso aberto
Palavra-chave:Drug-induced sleep endoscopy
success rate
obstructive sleep apnea
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spelling Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patientsPang KPBaptista PMOlszewska EBraverman ICarrasco-Llatas, MarinaKishore SChandra SYang HCWang CMZChan YHPang KAPang EBRotenberg BDrug-induced sleep endoscopysuccess rateobstructive sleep apneaObjectives/Hypothesis Our objective was to determine whether drug-induced sleep apnea (DISE) affects the successfulness of the surgical outcome. Study Design Prospective, seven-country, nonrandomized trial. Methods There were 326 consecutive obstructive sleep apnea (OSA) patients who had nose, palate, and/or tongue surgery included in the study. DISE was performed in only one group. Results There were 170 patients in the DISE group and 156 patients in no-DISE group. The mean preoperative body mass index (BMI) for the DISE group was 27.6 +/- 4.6, whereas in the no-DISE group it was 28.1 +/- 3.9 (P = .23). The mean preoperative systolic blood pressure (SBP) for the DISE group was 130.4 +/- 16.7, whereas in the no-DISE group it was 142.9 +/- 15.5 (P < .001). The mean preoperative diastolic blood pressure (DBP) for the DISE group was 81.4 +/- 9.7, whereas in the no-DISE group it was 89.1 +/- 9.7 (P < .001). The mean preoperative apnea-hypopnea index (AHI) for the DISE group was 32.6 +/- 18.8, whereas in the no-DISE group it was 33.7 +/- 19.6 (P = .61). The mean postoperative AHI for the DISE group was 15.9 +/- 12.6, whereas in the no-DISE group it was 13.2 +/- 8.8 (P = .023). The age-, gender-, BMI-adjusted percentage change in AHI for the DISE group was -48.4 +/- 31.9, whereas in the no-DISE group it was -59.8 +/- 18.6 (P < .001). The age-, gender-, and BMI-adjusted success rate for the DISE group was 66.5%, whereas in the no-DISE group it was 80.8% (P = .004). The age-, gender-, and BMI-adjusted change in SBP for the DISE group was -6.1 +/- 8.6, whereas in the no-DISE group it was -13.3 +/- 11.1 (P < .001). The age-, gender-, and BMI-adjusted change in DBP in the DISE group was -5.2 +/- 12.1, whereas in the no-DISE group it was -12.4 +/- 11.7 (P < .001). The mean age- and gender-adjusted change in BMI for the DISE group was -4.6 +/- 12.9, whereas in the no-DISE group it was -6.3 +/- 18.5 (P = .34). The Cohen effect of BMI on the overall AHI, lowest oxygen saturation, and blood pressure changes was 0.08. Conclusions DISE may not significantly affect surgical success in OSA. Level of Evidence 2c Laryngoscope, 130:551-555, 2020WILEY2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/3496LARYNGOSCOPEISSN: 0023852XISSNe: 15314995reponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p34962026-06-11T12:45:17Z
dc.title.none.fl_str_mv Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
title Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
spellingShingle Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
Pang KP
Drug-induced sleep endoscopy
success rate
obstructive sleep apnea
title_short Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
title_full Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
title_fullStr Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
title_full_unstemmed Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
title_sort Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients
dc.creator.none.fl_str_mv Pang KP
Baptista PM
Olszewska E
Braverman I
Carrasco-Llatas, Marina
Kishore S
Chandra S
Yang HC
Wang CMZ
Chan YH
Pang KA
Pang EB
Rotenberg B
author Pang KP
author_facet Pang KP
Baptista PM
Olszewska E
Braverman I
Carrasco-Llatas, Marina
Kishore S
Chandra S
Yang HC
Wang CMZ
Chan YH
Pang KA
Pang EB
Rotenberg B
author_role author
author2 Baptista PM
Olszewska E
Braverman I
Carrasco-Llatas, Marina
Kishore S
Chandra S
Yang HC
Wang CMZ
Chan YH
Pang KA
Pang EB
Rotenberg B
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Drug-induced sleep endoscopy
success rate
obstructive sleep apnea
topic Drug-induced sleep endoscopy
success rate
obstructive sleep apnea
description Objectives/Hypothesis Our objective was to determine whether drug-induced sleep apnea (DISE) affects the successfulness of the surgical outcome. Study Design Prospective, seven-country, nonrandomized trial. Methods There were 326 consecutive obstructive sleep apnea (OSA) patients who had nose, palate, and/or tongue surgery included in the study. DISE was performed in only one group. Results There were 170 patients in the DISE group and 156 patients in no-DISE group. The mean preoperative body mass index (BMI) for the DISE group was 27.6 +/- 4.6, whereas in the no-DISE group it was 28.1 +/- 3.9 (P = .23). The mean preoperative systolic blood pressure (SBP) for the DISE group was 130.4 +/- 16.7, whereas in the no-DISE group it was 142.9 +/- 15.5 (P < .001). The mean preoperative diastolic blood pressure (DBP) for the DISE group was 81.4 +/- 9.7, whereas in the no-DISE group it was 89.1 +/- 9.7 (P < .001). The mean preoperative apnea-hypopnea index (AHI) for the DISE group was 32.6 +/- 18.8, whereas in the no-DISE group it was 33.7 +/- 19.6 (P = .61). The mean postoperative AHI for the DISE group was 15.9 +/- 12.6, whereas in the no-DISE group it was 13.2 +/- 8.8 (P = .023). The age-, gender-, BMI-adjusted percentage change in AHI for the DISE group was -48.4 +/- 31.9, whereas in the no-DISE group it was -59.8 +/- 18.6 (P < .001). The age-, gender-, and BMI-adjusted success rate for the DISE group was 66.5%, whereas in the no-DISE group it was 80.8% (P = .004). The age-, gender-, and BMI-adjusted change in SBP for the DISE group was -6.1 +/- 8.6, whereas in the no-DISE group it was -13.3 +/- 11.1 (P < .001). The age-, gender-, and BMI-adjusted change in DBP in the DISE group was -5.2 +/- 12.1, whereas in the no-DISE group it was -12.4 +/- 11.7 (P < .001). The mean age- and gender-adjusted change in BMI for the DISE group was -4.6 +/- 12.9, whereas in the no-DISE group it was -6.3 +/- 18.5 (P = .34). The Cohen effect of BMI on the overall AHI, lowest oxygen saturation, and blood pressure changes was 0.08. Conclusions DISE may not significantly affect surgical success in OSA. Level of Evidence 2c Laryngoscope, 130:551-555, 2020
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/3496
url https://fisabio.portalinvestigacion.com/publicaciones/3496
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv WILEY
publisher.none.fl_str_mv WILEY
dc.source.none.fl_str_mv LARYNGOSCOPE
ISSN: 0023852X
ISSNe: 15314995
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
collection r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,223283

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