Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study

Introduction: The impact of alcohol consumption on health, particularly in low quantities, remains controversial. Our objective was to assess the association between alcohol volume and heavy episodic drinking (HED) with all-cause mortality, while minimizing many of the known methodological issues. M...

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Detalles Bibliográficos
Autores: Galan, Iñaki, Fontán, Julia, Ortiz Burgos, Cristina, Lopez-Cuadrado, Teresa, Tellez-Plaza, Maria, García-Esquinas, Esther
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/25365
Acceso en línea:https://hdl.handle.net/20.500.12105/25365
Access Level:acceso abierto
Palabra clave:Alcohol
Cohort study
Heavy episodic drinking
Mortality
Spain
Adolescent
Adult
Aged
Alcohol Drinking
Binge Drinking
Cause of Death
Female
Health Surveys
Humans
Longitudinal Studies
Male
Middle Aged
Proportional Hazards Models
Young Adult
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oai_identifier_str oai:repisalud.isciii.es:20.500.12105/25365
network_acronym_str ES
network_name_str España
repository_id_str
spelling Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based studyGalan, IñakiFontán, JuliaOrtiz Burgos, CristinaLopez-Cuadrado, TeresaTellez-Plaza, MariaGarcía-Esquinas, EstherAlcoholCohort studyHeavy episodic drinkingMortalitySpainAdolescentAdultAgedAlcohol DrinkingBinge DrinkingCause of DeathFemaleHealth SurveysHumansLongitudinal StudiesMaleMiddle AgedMortalityProportional Hazards ModelsSpainYoung AdultIntroduction: The impact of alcohol consumption on health, particularly in low quantities, remains controversial. Our objective was to assess the association between alcohol volume and heavy episodic drinking (HED) with all-cause mortality, while minimizing many of the known methodological issues. Methodology: This longitudinal study used data from the 2011-2012 National Health Survey and the 2014 European Health Survey in Spain. Data from 43,071 participants aged ≥ 15 years were linked to mortality records as of December 2021. Alcohol consumption categories were defined based on intake volume and frequency: never-drinkers, former drinkers, infrequent occasional drinkers (≤once/month), frequent occasional drinkers (<once/week to > once /month). Regular drinkers (≥once/week) were further classified by volume: >0-10 g/day, >10-20 g/day, >20-40 g/day, and > 40 g/day. Heavy Episodic Drinking (HED) was defined as ≥ 6 and ≥ 5 standard drinks (10 g) within 4-6 h for men and women, respectively. Hazard ratios (HR) were calculated using Cox regression, adjusting for sociodemographic variables, lifestyle factors, health status, and alcohol volume or HED. Results: Compared to infrequent occasional drinkers, HRs for never-drinkers and former drinkers were 1.30 (95 %CI:1.14-1.47) and 1.32 (95 %CI:1.15-1.50), respectively. No differences in mortality risk were observed for intakes up to 20 g/day, but it increased for consumptions > 20-40 g/day and > 40 g/day (HR = 1.29; 95 %CI:1.05-1.58 and HR = 1.57; 95 %CI:1.14-2.17, respectively). The HR of weekly HED vs. never was 1.31 (95 %CI:0.98-1.75). Conclusions: Compared to infrequent occasional drinking, consuming low amounts of alcohol had no impact on mortality risk. However, never-drinkers, former drinkers, individuals with regular consumption > 20 g/day, and those engaging in weekly HED, experienced higher mortality risk.ElsevierMinisterio de Sanidad (España)Plan Nacional de Drogas (España)20242024-10-2920242024-11-0120242024-11-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://hdl.handle.net/20.500.12105/25365reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)InglésengES PI2021I033 Not availableopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/253652026-06-12T12:43:37Z
dc.title.none.fl_str_mv Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
title Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
spellingShingle Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
Galan, Iñaki
Alcohol
Cohort study
Heavy episodic drinking
Mortality
Spain
Adolescent
Adult
Aged
Alcohol Drinking
Binge Drinking
Cause of Death
Female
Health Surveys
Humans
Longitudinal Studies
Male
Middle Aged
Mortality
Proportional Hazards Models
Spain
Young Adult
title_short Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
title_full Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
title_fullStr Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
title_full_unstemmed Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
title_sort Volume of alcohol intake, heavy episodic drinking, and all-cause mortality in Spain: A longitudinal population-based study
dc.creator.none.fl_str_mv Galan, Iñaki
Fontán, Julia
Ortiz Burgos, Cristina
Lopez-Cuadrado, Teresa
Tellez-Plaza, Maria
García-Esquinas, Esther
author Galan, Iñaki
author_facet Galan, Iñaki
Fontán, Julia
Ortiz Burgos, Cristina
Lopez-Cuadrado, Teresa
Tellez-Plaza, Maria
García-Esquinas, Esther
author_role author
author2 Fontán, Julia
Ortiz Burgos, Cristina
Lopez-Cuadrado, Teresa
Tellez-Plaza, Maria
García-Esquinas, Esther
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Sanidad (España)
Plan Nacional de Drogas (España)
dc.subject.none.fl_str_mv Alcohol
Cohort study
Heavy episodic drinking
Mortality
Spain
Adolescent
Adult
Aged
Alcohol Drinking
Binge Drinking
Cause of Death
Female
Health Surveys
Humans
Longitudinal Studies
Male
Middle Aged
Mortality
Proportional Hazards Models
Spain
Young Adult
topic Alcohol
Cohort study
Heavy episodic drinking
Mortality
Spain
Adolescent
Adult
Aged
Alcohol Drinking
Binge Drinking
Cause of Death
Female
Health Surveys
Humans
Longitudinal Studies
Male
Middle Aged
Mortality
Proportional Hazards Models
Spain
Young Adult
description Introduction: The impact of alcohol consumption on health, particularly in low quantities, remains controversial. Our objective was to assess the association between alcohol volume and heavy episodic drinking (HED) with all-cause mortality, while minimizing many of the known methodological issues. Methodology: This longitudinal study used data from the 2011-2012 National Health Survey and the 2014 European Health Survey in Spain. Data from 43,071 participants aged ≥ 15 years were linked to mortality records as of December 2021. Alcohol consumption categories were defined based on intake volume and frequency: never-drinkers, former drinkers, infrequent occasional drinkers (≤once/month), frequent occasional drinkers (<once/week to > once /month). Regular drinkers (≥once/week) were further classified by volume: >0-10 g/day, >10-20 g/day, >20-40 g/day, and > 40 g/day. Heavy Episodic Drinking (HED) was defined as ≥ 6 and ≥ 5 standard drinks (10 g) within 4-6 h for men and women, respectively. Hazard ratios (HR) were calculated using Cox regression, adjusting for sociodemographic variables, lifestyle factors, health status, and alcohol volume or HED. Results: Compared to infrequent occasional drinkers, HRs for never-drinkers and former drinkers were 1.30 (95 %CI:1.14-1.47) and 1.32 (95 %CI:1.15-1.50), respectively. No differences in mortality risk were observed for intakes up to 20 g/day, but it increased for consumptions > 20-40 g/day and > 40 g/day (HR = 1.29; 95 %CI:1.05-1.58 and HR = 1.57; 95 %CI:1.14-2.17, respectively). The HR of weekly HED vs. never was 1.31 (95 %CI:0.98-1.75). Conclusions: Compared to infrequent occasional drinking, consuming low amounts of alcohol had no impact on mortality risk. However, never-drinkers, former drinkers, individuals with regular consumption > 20 g/day, and those engaging in weekly HED, experienced higher mortality risk.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-10-29
2024
2024-11-01
2024
2024-11-01
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.12105/25365
url https://hdl.handle.net/20.500.12105/25365
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv ES PI2021I033 Not available
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869419322243284992
score 15,812455

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