Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain

Chlamydia trachomatis; OmpA genotyping; Sexual behaviour

Detalles Bibliográficos
Autores: Piñeiro, Luis, VILLA, LAURA, Salmeron, Paula, Macia, Maria Dolores, Otero, Luis, Vall Mayans, Martí
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:11351/9483
Acceso en línea:https://hdl.handle.net/11351/9483
http://hdl.handle.net/11351/9483
Access Level:acceso abierto
Palabra clave:Malalties de transmissió sexual - Epidemiologia
Infeccions per clamídia - Epidemiologia
Genotip
Other subheadings::Other subheadings::Other subheadings::/epidemiology
PHENOMENA AND PROCESSES::Genetic Phenomena::Genotype
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Sexually Transmitted Diseases, Bacterial
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Chlamydiaceae Infections::Chlamydia Infections
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias gramnegativas::infecciones por Chlamydiaceae::infecciones por Chlamydia
Otros calificadores::Otros calificadores::Otros calificadores::/epidemiología
FENÓMENOS Y PROCESOS::fenómenos genéticos::genotipo
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::enfermedades bacterianas de transmisión sexual
id ES_c80e0ad9bc0112bd69428ec8bcc6436e
oai_identifier_str oai:recercat.cat:11351/9483
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
title Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
spellingShingle Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
Piñeiro, Luis
Malalties de transmissió sexual - Epidemiologia
Infeccions per clamídia - Epidemiologia
Genotip
Other subheadings::Other subheadings::Other subheadings::/epidemiology
PHENOMENA AND PROCESSES::Genetic Phenomena::Genotype
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Sexually Transmitted Diseases, Bacterial
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Chlamydiaceae Infections::Chlamydia Infections
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias gramnegativas::infecciones por Chlamydiaceae::infecciones por Chlamydia
Otros calificadores::Otros calificadores::Otros calificadores::/epidemiología
FENÓMENOS Y PROCESOS::fenómenos genéticos::genotipo
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::enfermedades bacterianas de transmisión sexual
title_short Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
title_full Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
title_fullStr Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
title_full_unstemmed Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
title_sort Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in Spain
dc.creator.none.fl_str_mv Piñeiro, Luis
VILLA, LAURA
Salmeron, Paula
Macia, Maria Dolores
Otero, Luis
Vall Mayans, Martí
author Piñeiro, Luis
author_facet Piñeiro, Luis
VILLA, LAURA
Salmeron, Paula
Macia, Maria Dolores
Otero, Luis
Vall Mayans, Martí
author_role author
author2 VILLA, LAURA
Salmeron, Paula
Macia, Maria Dolores
Otero, Luis
Vall Mayans, Martí
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Institut Català de la Salut
[Piñeiro L] Microbiology Department, Donostia University Hospital-Biodonostia Health Research Institute, San Sebastian, Spain. Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. [Villa L] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Microbiology Department, Central University Hospital of Asturias, Oviedo, Spain. [Salmerón P] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Maciá MD] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Microbiology Department, Son Espases University Hospital, Palma de Mallorca, Spain. [Otero L] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Microbiology Department, Cabueñes University Hospital, Gijón, Spain. [Vall-Mayans M] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Unitat d’Infeccions de Transmissió Sexual, Servei de Malalties Infeccioses, Centre de Salut Internacional i Malalties transmissibles Drassanes-Vall d’Hebron Hospital Universitari, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
dc.subject.none.fl_str_mv Malalties de transmissió sexual - Epidemiologia
Infeccions per clamídia - Epidemiologia
Genotip
Other subheadings::Other subheadings::Other subheadings::/epidemiology
PHENOMENA AND PROCESSES::Genetic Phenomena::Genotype
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Sexually Transmitted Diseases, Bacterial
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Chlamydiaceae Infections::Chlamydia Infections
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias gramnegativas::infecciones por Chlamydiaceae::infecciones por Chlamydia
Otros calificadores::Otros calificadores::Otros calificadores::/epidemiología
FENÓMENOS Y PROCESOS::fenómenos genéticos::genotipo
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::enfermedades bacterianas de transmisión sexual
topic Malalties de transmissió sexual - Epidemiologia
Infeccions per clamídia - Epidemiologia
Genotip
Other subheadings::Other subheadings::Other subheadings::/epidemiology
PHENOMENA AND PROCESSES::Genetic Phenomena::Genotype
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Sexually Transmitted Diseases, Bacterial
DISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Chlamydiaceae Infections::Chlamydia Infections
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias gramnegativas::infecciones por Chlamydiaceae::infecciones por Chlamydia
Otros calificadores::Otros calificadores::Otros calificadores::/epidemiología
FENÓMENOS Y PROCESOS::fenómenos genéticos::genotipo
ENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::enfermedades bacterianas de transmisión sexual
description Chlamydia trachomatis; OmpA genotyping; Sexual behaviour
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11351/9483
http://hdl.handle.net/11351/9483
url https://hdl.handle.net/11351/9483
http://hdl.handle.net/11351/9483
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv International Journal of Molecular Sciences;24(8)
https://doi.org/10.3390/ijms24086941
dc.rights.none.fl_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Scientia
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling Genetic Characterization of Non-Lymphogranuloma venereum Chlamydia trachomatis Indicates Distinct Infection Transmission Networks in SpainPiñeiro, LuisVILLA, LAURASalmeron, PaulaMacia, Maria DoloresOtero, LuisVall Mayans, MartíMalalties de transmissió sexual - EpidemiologiaInfeccions per clamídia - EpidemiologiaGenotipOther subheadings::Other subheadings::Other subheadings::/epidemiologyPHENOMENA AND PROCESSES::Genetic Phenomena::GenotypeDISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Sexually Transmitted Diseases, BacterialDISEASES::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Chlamydiaceae Infections::Chlamydia InfectionsENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::infecciones por bacterias gramnegativas::infecciones por Chlamydiaceae::infecciones por ChlamydiaOtros calificadores::Otros calificadores::Otros calificadores::/epidemiologíaFENÓMENOS Y PROCESOS::fenómenos genéticos::genotipoENFERMEDADES::infecciones bacterianas y micosis::infecciones bacterianas::enfermedades bacterianas de transmisión sexualChlamydia trachomatis; OmpA genotyping; Sexual behaviourChlamydia trachomatis; Genotipado ompA; Comportamiento sexualChlamydia trachomatis; Genotipat ompA; Comportament sexualChlamydia trachomatis infection is an important public health problem. Our objective was to assess the dynamics of the transmission of this infection, analysing the distribution of circulating ompA genotypes and multilocus sequence types of C. trachomatis in Spain as a function of clinical and epidemiological variables. During 2018 and 2019, we genetically characterized C. trachomatis in tertiary hospitals in six areas in Spain (Asturias, Barcelona, Gipuzkoa, Mallorca, Seville and Zaragoza), with a catchment population of 3.050 million people. Genotypes and sequence types were obtained using polymerase chain reaction techniques that amplify a fragment of the ompA gene, and five highly variable genes (hctB, CT058, CT144, CT172 and pbpB), respectively. Amplicons were sequenced and phylogenetic analysis was conducted. We obtained genotypes in 636/698 cases (91.1%). Overall and by area, genotype E was the most common (35%). Stratifying by sex, genotypes D and G were more common among men, and genotypes F and I among women (p < 0.05). Genotypes D, G and J were more common in men who have sex with men (MSM) than in men who have sex with women (MSW), in whom the most common genotypes were E and F. The diversity index was higher in sequence typing (0.981) than in genotyping (0.791), and the most common sequence types were ST52 and ST108 in MSM, and ST30, ST148, ST276 and ST327 in MSW. Differences in genotype distribution between geographical areas were attributable to differences in population characteristics. The transmission dynamics varied with sexual behaviour: the predominant genotypes and most frequent sequence types found in MSM were different to those detected in MSW and women.This study was funded by Instituto de Salud Carlos III (ISCIII) through the project “PI17/01886”, and co-funded by the European Union.MDPIInstitut Català de la Salut[Piñeiro L] Microbiology Department, Donostia University Hospital-Biodonostia Health Research Institute, San Sebastian, Spain. Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. [Villa L] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Microbiology Department, Central University Hospital of Asturias, Oviedo, Spain. [Salmerón P] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Servei de Microbiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Maciá MD] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Microbiology Department, Son Espases University Hospital, Palma de Mallorca, Spain. [Otero L] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Microbiology Department, Cabueñes University Hospital, Gijón, Spain. [Vall-Mayans M] Sexually Transmitted Infections Study Group of the Infectious Diseases and Clinical Microbiology Spanish Society (GEITS-SEIMC), Madrid, Spain. Unitat d’Infeccions de Transmissió Sexual, Servei de Malalties Infeccioses, Centre de Salut Internacional i Malalties transmissibles Drassanes-Vall d’Hebron Hospital Universitari, Barcelona, SpainVall d'Hebron Barcelona Hospital Campus202320232023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11351/9483http://hdl.handle.net/11351/9483Scientiareponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésInternational Journal of Molecular Sciences;24(8)https://doi.org/10.3390/ijms24086941Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:11351/94832026-05-29T05:05:01Z
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