The Diagnosis of Polycystic Ovary Syndrome during Adolescence

Background/Aims: The diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescence are controversial, primarily because the diagnostic pathological features used in adult women may be normal pubertal physiological events. Hence, international pediatric and adolescent specialty societies ha...

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Autores: Witchel SF, Oberfield S, Rosenfield RL, Codner E, Bonny A, Ibáñez L, Pena A, Horikawa R, Gomez-Lobo V, Joel D, Tfayli H, Arslanian S, Dabdghao P, Garcia Rudaz C, Lee PA
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p7627
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7627
Access Level:acceso abierto
Palabra clave:Hyperandrogenism
Ovarian hyperandrogenism
Ovary
Polycystic ovary syndrome
Puberty
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spelling The Diagnosis of Polycystic Ovary Syndrome during AdolescenceWitchel SFOberfield SRosenfield RLCodner EBonny AIbáñez LPena AHorikawa RGomez-Lobo VJoel DTfayli HArslanian SDabdghao PGarcia Rudaz CLee PAHyperandrogenismOvarian hyperandrogenismOvaryPolycystic ovary syndromePubertyBackground/Aims: The diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescence are controversial, primarily because the diagnostic pathological features used in adult women may be normal pubertal physiological events. Hence, international pediatric and adolescent specialty societies have defined criteria that have sufficient evidence to be used for the diagnosis of PCOS in adolescents. Methods: The literature has been reviewed and evidence graded to address a series of questions regarding the diagnosis of PCOS during adolescence including the following: clinical and biochemical evidence of hyperandrogenism, criteria for oligo-anovulation and polycystic ovary morphology, diagnostic criteria to exclude other causes of hyperandrogenism and amenorrhea, role of insulin resistance, and intervention. Results and Conclusion: Features of PCOS overlap normal pubertal development. Hence, caution should be taken before diagnosing PCOS without longitudinal evaluation. However, treatment may be indicated even in the absence of a definitive diagnosis. While obesity, insulin resistance, and hyperinsulinemia are common findings in adolescents with hyperandrogenism, these features should not be used to diagnose PCOS among adolescent girls. (C) 2015 S. Karger AG, BaselKARGER2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7627Hormone Research in PaediatricsISSN: 16632818ISSNe: 16632826reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p76272026-05-27T12:37:41Z
dc.title.none.fl_str_mv The Diagnosis of Polycystic Ovary Syndrome during Adolescence
title The Diagnosis of Polycystic Ovary Syndrome during Adolescence
spellingShingle The Diagnosis of Polycystic Ovary Syndrome during Adolescence
Witchel SF
Hyperandrogenism
Ovarian hyperandrogenism
Ovary
Polycystic ovary syndrome
Puberty
title_short The Diagnosis of Polycystic Ovary Syndrome during Adolescence
title_full The Diagnosis of Polycystic Ovary Syndrome during Adolescence
title_fullStr The Diagnosis of Polycystic Ovary Syndrome during Adolescence
title_full_unstemmed The Diagnosis of Polycystic Ovary Syndrome during Adolescence
title_sort The Diagnosis of Polycystic Ovary Syndrome during Adolescence
dc.creator.none.fl_str_mv Witchel SF
Oberfield S
Rosenfield RL
Codner E
Bonny A
Ibáñez L
Pena A
Horikawa R
Gomez-Lobo V
Joel D
Tfayli H
Arslanian S
Dabdghao P
Garcia Rudaz C
Lee PA
author Witchel SF
author_facet Witchel SF
Oberfield S
Rosenfield RL
Codner E
Bonny A
Ibáñez L
Pena A
Horikawa R
Gomez-Lobo V
Joel D
Tfayli H
Arslanian S
Dabdghao P
Garcia Rudaz C
Lee PA
author_role author
author2 Oberfield S
Rosenfield RL
Codner E
Bonny A
Ibáñez L
Pena A
Horikawa R
Gomez-Lobo V
Joel D
Tfayli H
Arslanian S
Dabdghao P
Garcia Rudaz C
Lee PA
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Hyperandrogenism
Ovarian hyperandrogenism
Ovary
Polycystic ovary syndrome
Puberty
topic Hyperandrogenism
Ovarian hyperandrogenism
Ovary
Polycystic ovary syndrome
Puberty
description Background/Aims: The diagnostic criteria for polycystic ovary syndrome (PCOS) in adolescence are controversial, primarily because the diagnostic pathological features used in adult women may be normal pubertal physiological events. Hence, international pediatric and adolescent specialty societies have defined criteria that have sufficient evidence to be used for the diagnosis of PCOS in adolescents. Methods: The literature has been reviewed and evidence graded to address a series of questions regarding the diagnosis of PCOS during adolescence including the following: clinical and biochemical evidence of hyperandrogenism, criteria for oligo-anovulation and polycystic ovary morphology, diagnostic criteria to exclude other causes of hyperandrogenism and amenorrhea, role of insulin resistance, and intervention. Results and Conclusion: Features of PCOS overlap normal pubertal development. Hence, caution should be taken before diagnosing PCOS without longitudinal evaluation. However, treatment may be indicated even in the absence of a definitive diagnosis. While obesity, insulin resistance, and hyperinsulinemia are common findings in adolescents with hyperandrogenism, these features should not be used to diagnose PCOS among adolescent girls. (C) 2015 S. Karger AG, Basel
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7627
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7627
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv KARGER
publisher.none.fl_str_mv KARGER
dc.source.none.fl_str_mv Hormone Research in Paediatrics
ISSN: 16632818
ISSNe: 16632826
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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