Suicidality among people with mild cognitive impairment: a systematic review

[ENG]Background: Mild cognitive impairment (MCI) is a clinical stage between the expected cognitive decline of healthy ageing and dementia. People with MCI experience functional decline, social isolation and emotional symptoms that may increase suicidal thoughts and behaviours (STB). We aimed to exp...

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Autores: Sánchez Gil, Alba, Pérez, Jesús, Navarro López, Víctor, Sánchez González, Juan Luis
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/170717
Acceso en línea:http://hdl.handle.net/10366/170717
Access Level:acceso abierto
Palabra clave:MCI
Mild cognitive impairment
Systematic review
Mortality
Suicide
Mild Cognitive Impairment
deficiencia cognitiva leve
mortalidad
suicidio
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spelling Suicidality among people with mild cognitive impairment: a systematic reviewSánchez Gil, AlbaPérez, JesúsNavarro López, VíctorSánchez González, Juan LuisMCIMild cognitive impairmentSystematic reviewMortalitySuicideMortalitySuicideMild Cognitive Impairmentdeficiencia cognitiva levemortalidadsuicidio[ENG]Background: Mild cognitive impairment (MCI) is a clinical stage between the expected cognitive decline of healthy ageing and dementia. People with MCI experience functional decline, social isolation and emotional symptoms that may increase suicidal thoughts and behaviours (STB). We aimed to explore the relationship between MCI and STB, as well as clinical and socioeconomic factors that may contribute to it. Methods: To achieve our aims we carried out a comprensive systematic review of the existing scientific literature. We searched the following electronic databases up to June 2024: PubMed, Scopus, Cochrane Library, Web Of Science (WOS) and EMBASE. We employed the Cochrane Risk of Bias In Non-randomized Studies - of Exposure (ROBINS-E) and the Newcastle-Ottawa Scale to assess the quality of the eligible studies. Results: An initial search retrieved 1,176 publications; however, only 11 studies met eligibility criteria to be included in the final analysis. The quality of these studies ranged from 3 to 8 out of a maximum score of 9 in the Newcastle-Ottawa Scale, with a median score of 6. People with a formal diagnosis of MCI showed a higher prevalence of STB than those without such condition or with a more severe cognitive impairment. Comorbid psychiatric disorders, such as depression, other health problems, such as cardiovascular diseases, and a low socioeconomic status and/or poor educational background seemed to contribute to suicide risk in people with MCI. Conclusion: Our systematic review suggests that people suffering MCI may be at an increased risk of presenting STB. Suicide prevention programmes for older populations with MCI should advocate for integrated health and social care models to tackle the clinical and social burden of suffering MCI.https://link.springer.com/article/10.1186/s12888-025-07228-x202620262025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10366/170717reponame:GREDOS. Repositorio Institucional de la Universidad de Salamancainstname:Universidad de Salamanca (USAL)InglésAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:gredos.usal.es:10366/1707172026-06-07T06:28:51Z
dc.title.none.fl_str_mv Suicidality among people with mild cognitive impairment: a systematic review
title Suicidality among people with mild cognitive impairment: a systematic review
spellingShingle Suicidality among people with mild cognitive impairment: a systematic review
Sánchez Gil, Alba
MCI
Mild cognitive impairment
Systematic review
Mortality
Suicide
Mortality
Suicide
Mild Cognitive Impairment
deficiencia cognitiva leve
mortalidad
suicidio
title_short Suicidality among people with mild cognitive impairment: a systematic review
title_full Suicidality among people with mild cognitive impairment: a systematic review
title_fullStr Suicidality among people with mild cognitive impairment: a systematic review
title_full_unstemmed Suicidality among people with mild cognitive impairment: a systematic review
title_sort Suicidality among people with mild cognitive impairment: a systematic review
dc.creator.none.fl_str_mv Sánchez Gil, Alba
Pérez, Jesús
Navarro López, Víctor
Sánchez González, Juan Luis
author Sánchez Gil, Alba
author_facet Sánchez Gil, Alba
Pérez, Jesús
Navarro López, Víctor
Sánchez González, Juan Luis
author_role author
author2 Pérez, Jesús
Navarro López, Víctor
Sánchez González, Juan Luis
author2_role author
author
author
dc.subject.none.fl_str_mv MCI
Mild cognitive impairment
Systematic review
Mortality
Suicide
Mortality
Suicide
Mild Cognitive Impairment
deficiencia cognitiva leve
mortalidad
suicidio
topic MCI
Mild cognitive impairment
Systematic review
Mortality
Suicide
Mortality
Suicide
Mild Cognitive Impairment
deficiencia cognitiva leve
mortalidad
suicidio
description [ENG]Background: Mild cognitive impairment (MCI) is a clinical stage between the expected cognitive decline of healthy ageing and dementia. People with MCI experience functional decline, social isolation and emotional symptoms that may increase suicidal thoughts and behaviours (STB). We aimed to explore the relationship between MCI and STB, as well as clinical and socioeconomic factors that may contribute to it. Methods: To achieve our aims we carried out a comprensive systematic review of the existing scientific literature. We searched the following electronic databases up to June 2024: PubMed, Scopus, Cochrane Library, Web Of Science (WOS) and EMBASE. We employed the Cochrane Risk of Bias In Non-randomized Studies - of Exposure (ROBINS-E) and the Newcastle-Ottawa Scale to assess the quality of the eligible studies. Results: An initial search retrieved 1,176 publications; however, only 11 studies met eligibility criteria to be included in the final analysis. The quality of these studies ranged from 3 to 8 out of a maximum score of 9 in the Newcastle-Ottawa Scale, with a median score of 6. People with a formal diagnosis of MCI showed a higher prevalence of STB than those without such condition or with a more severe cognitive impairment. Comorbid psychiatric disorders, such as depression, other health problems, such as cardiovascular diseases, and a low socioeconomic status and/or poor educational background seemed to contribute to suicide risk in people with MCI. Conclusion: Our systematic review suggests that people suffering MCI may be at an increased risk of presenting STB. Suicide prevention programmes for older populations with MCI should advocate for integrated health and social care models to tackle the clinical and social burden of suffering MCI.
publishDate 2025
dc.date.none.fl_str_mv 2025
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10366/170717
url http://hdl.handle.net/10366/170717
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv https://link.springer.com/article/10.1186/s12888-025-07228-x
publisher.none.fl_str_mv https://link.springer.com/article/10.1186/s12888-025-07228-x
dc.source.none.fl_str_mv reponame:GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname:Universidad de Salamanca (USAL)
instname_str Universidad de Salamanca (USAL)
reponame_str GREDOS. Repositorio Institucional de la Universidad de Salamanca
collection GREDOS. Repositorio Institucional de la Universidad de Salamanca
repository.name.fl_str_mv
repository.mail.fl_str_mv
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