Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry

Introduction and objectives: Coronary lesions with stent overlapping are associated with higher neointimal proliferation that leads to more restenosis. Furthermore, the tapering of coronary arteries is a major challenge when treating long coronary lesions. This study attempted to assess the safety a...

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Autores: Domingo Ribas, Enric, Guindo Soldevila, Josep, Calviño Santos, Ramón, Otaegui, Imanol, Gómez, Joan Antoni, Carrillo Suárez, Xavier, Sánchez, Juan, Andraka, Leire, Torres, Alfonso, Casanova Sandoval, Juan, Ocaranza Sánchez, Raymundo, León Jiménez, Javier, Muñoz, Juan Francisco, Trillo Nouche, Ramiro, Fuertes, Mónica, García del Blanco, Bruno
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/193101
Acesso em linha:https://hdl.handle.net/2445/193101
Access Level:acceso abierto
Palavra-chave:Malalties coronàries
Pròtesis de Stent
Coronary diseases
Stents (Surgery)
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spelling Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registryDomingo Ribas, EnricGuindo Soldevila, JosepCalviño Santos, RamónOtaegui, ImanolGómez, Joan AntoniCarrillo Suárez, XavierSánchez, JuanAndraka, LeireTorres, AlfonsoCasanova Sandoval, JuanOcaranza Sánchez, RaymundoLeón Jiménez, JavierMuñoz, Juan FranciscoTrillo Nouche, RamiroFuertes, MónicaGarcía del Blanco, BrunoMalalties coronàriesPròtesis de StentCoronary diseasesStents (Surgery)Introduction and objectives: Coronary lesions with stent overlapping are associated with higher neointimal proliferation that leads to more restenosis. Furthermore, the tapering of coronary arteries is a major challenge when treating long coronary lesions. This study attempted to assess the safety and clinical level of performance of long nontapered sirolimus-eluting coronary stent systems (> 36 mm) to treat long and diffused de novo coronary lesions in real-world scenarios. Methods: This was a prospective, non-randomized, multicentre study that included 696 consecutive patients treated with the long nontapered BioMime sirolimus-eluting coronary stent system in long and diffused de novo coronary lesions. The safety endpoint was major adverse cardiovascular events defined as a composite of cardiac death, myocardial infarction, clinically driven target lesion revascularization, stent thrombosis, and major bleeding at the 12-month follow-up. Results: Of a total of 696 patients, 38.79% were diabetic. The mean age of all the patients was 64.6 +/- 14 years, and 80% were males. The indication for revascularization was acute coronary syndrome in 63.1%. A total of 899 lesions were identified out of which 742 were successfully treated with long BioMime stents (37 mm, 40 mm, 44 mm, and 48 mm). The cumulative incidence of major adverse cardiovascular events was 8.1% at the 12-month follow-up including cardiac death (2.09%), myocardial infarction (1.34%), and total stent thrombosis (0.5%). Conclusions: This study confirms the safety and good performance of long nontapered BioMime coronary stents to treat de novo coronary stenosis. Therefore, it can be considered a safe and effective treatment for long and diffused de novo coronary lesions in the routine clinical practice.Publicidad Permanyer, SLU2023202320212023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion6 p.application/pdfhttps://hdl.handle.net/2445/193101Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.24875/RECICE.M21000251REC: interventional cardiology (English Edition), 2022, vol. 4, num. 1, p. 27-32https://doi.org/10.24875/RECICE.M21000251cc by-nc-nd (c) Domingo Ribas, Enric et al., 2022http://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1931012026-05-29T05:05:01Z
dc.title.none.fl_str_mv Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
title Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
spellingShingle Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
Domingo Ribas, Enric
Malalties coronàries
Pròtesis de Stent
Coronary diseases
Stents (Surgery)
title_short Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
title_full Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
title_fullStr Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
title_full_unstemmed Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
title_sort Clinical follow-up of long nontapered sirolimus-eluting coronary stent in real-world patients with de novo lesions. The Billar registry
dc.creator.none.fl_str_mv Domingo Ribas, Enric
Guindo Soldevila, Josep
Calviño Santos, Ramón
Otaegui, Imanol
Gómez, Joan Antoni
Carrillo Suárez, Xavier
Sánchez, Juan
Andraka, Leire
Torres, Alfonso
Casanova Sandoval, Juan
Ocaranza Sánchez, Raymundo
León Jiménez, Javier
Muñoz, Juan Francisco
Trillo Nouche, Ramiro
Fuertes, Mónica
García del Blanco, Bruno
author Domingo Ribas, Enric
author_facet Domingo Ribas, Enric
Guindo Soldevila, Josep
Calviño Santos, Ramón
Otaegui, Imanol
Gómez, Joan Antoni
Carrillo Suárez, Xavier
Sánchez, Juan
Andraka, Leire
Torres, Alfonso
Casanova Sandoval, Juan
Ocaranza Sánchez, Raymundo
León Jiménez, Javier
Muñoz, Juan Francisco
Trillo Nouche, Ramiro
Fuertes, Mónica
García del Blanco, Bruno
author_role author
author2 Guindo Soldevila, Josep
Calviño Santos, Ramón
Otaegui, Imanol
Gómez, Joan Antoni
Carrillo Suárez, Xavier
Sánchez, Juan
Andraka, Leire
Torres, Alfonso
Casanova Sandoval, Juan
Ocaranza Sánchez, Raymundo
León Jiménez, Javier
Muñoz, Juan Francisco
Trillo Nouche, Ramiro
Fuertes, Mónica
García del Blanco, Bruno
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Malalties coronàries
Pròtesis de Stent
Coronary diseases
Stents (Surgery)
topic Malalties coronàries
Pròtesis de Stent
Coronary diseases
Stents (Surgery)
description Introduction and objectives: Coronary lesions with stent overlapping are associated with higher neointimal proliferation that leads to more restenosis. Furthermore, the tapering of coronary arteries is a major challenge when treating long coronary lesions. This study attempted to assess the safety and clinical level of performance of long nontapered sirolimus-eluting coronary stent systems (> 36 mm) to treat long and diffused de novo coronary lesions in real-world scenarios. Methods: This was a prospective, non-randomized, multicentre study that included 696 consecutive patients treated with the long nontapered BioMime sirolimus-eluting coronary stent system in long and diffused de novo coronary lesions. The safety endpoint was major adverse cardiovascular events defined as a composite of cardiac death, myocardial infarction, clinically driven target lesion revascularization, stent thrombosis, and major bleeding at the 12-month follow-up. Results: Of a total of 696 patients, 38.79% were diabetic. The mean age of all the patients was 64.6 +/- 14 years, and 80% were males. The indication for revascularization was acute coronary syndrome in 63.1%. A total of 899 lesions were identified out of which 742 were successfully treated with long BioMime stents (37 mm, 40 mm, 44 mm, and 48 mm). The cumulative incidence of major adverse cardiovascular events was 8.1% at the 12-month follow-up including cardiac death (2.09%), myocardial infarction (1.34%), and total stent thrombosis (0.5%). Conclusions: This study confirms the safety and good performance of long nontapered BioMime coronary stents to treat de novo coronary stenosis. Therefore, it can be considered a safe and effective treatment for long and diffused de novo coronary lesions in the routine clinical practice.
publishDate 2021
dc.date.none.fl_str_mv 2021
2023
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/193101
url https://hdl.handle.net/2445/193101
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.24875/RECICE.M21000251
REC: interventional cardiology (English Edition), 2022, vol. 4, num. 1, p. 27-32
https://doi.org/10.24875/RECICE.M21000251
dc.rights.none.fl_str_mv cc by-nc-nd (c) Domingo Ribas, Enric et al., 2022
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by-nc-nd (c) Domingo Ribas, Enric et al., 2022
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 6 p.
application/pdf
dc.publisher.none.fl_str_mv Publicidad Permanyer, SLU
publisher.none.fl_str_mv Publicidad Permanyer, SLU
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418336921583617
score 15,198674

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