Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke

In a pilot study on acute ischemic stroke (AIS) patients, unexpected periodic fluctuations in microvascular cerebral blood flow (CBF) had been observed. Motivated by the relative lack of information about the impact of the emergence of breathing disorders in association with stroke on cerebral hemod...

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Autores: Gregori-Pla, C, Delgado-Mederos, R, Cotta, G, Giacalone, G, Maruccia, F, Avtzi, S, Prats-Sanchez, L, Martinez-Domeno, A, Camps-Renom, P, Marti-Fabregas, J, Durduran, T, Mayos, M
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Recursos:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p2778
Acesso em linha:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2778
http://ddd.uab.cat/record/222720
Access Level:acceso abierto
Palavra-chave:diffuse optics
diffuse correlation spectroscopy
stroke
sleep disorders
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spelling Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic strokeGregori-Pla, CDelgado-Mederos, RCotta, GGiacalone, GMaruccia, FAvtzi, SPrats-Sanchez, LMartinez-Domeno, ACamps-Renom, PMarti-Fabregas, JDurduran, TMayos, Mdiffuse opticsdiffuse correlation spectroscopystrokesleep disordersIn a pilot study on acute ischemic stroke (AIS) patients, unexpected periodic fluctuations in microvascular cerebral blood flow (CBF) had been observed. Motivated by the relative lack of information about the impact of the emergence of breathing disorders in association with stroke on cerebral hemodynamics, we hypothesized that these fluctuations are due to apneic and hypopneic events. A total of 28 patients were screened within the first week after stroke with a pulse oximeter. Five (18%) showed fluctuations of arterial blood oxygen saturation (>= 3 % ) and were included in the study. Near-infrared diffuse correlation spectroscopy (DCS) was utilized bilaterally to measure the frontal lobe CBF alongside respiratory polygraphy. Biphasic CBF fluctuations were observed with a bilateral increase of 27.1 % +/- 17.7 % and 29.0 % +/- 17.4 % for the ipsilesional and contralesional hemispheres, respectively, and a decrease of -19.3 % +/- 9.1 % and -21.0 % +/- 8.9 % for the ipsilesional and contralesional hemispheres, respectively. The polygraph revealed that, in general, the fluctuations were associated with apneic and hypopneic events. This study motivates us to investigate whether the impact of altered respiratory patterns on cerebral hemodynamics can be detrimental in AIS patients. patients. (C) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License.SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2778http://ddd.uab.cat/record/222720NeurophotonicsISSN: 2329423XISSNe: 23294248reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauinstname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)Inglésinfo:eu-repo/semantics/openAccessoai:iibsantpau.fundanetsuite.com:p27782026-06-14T12:41:47Z
dc.title.none.fl_str_mv Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
title Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
spellingShingle Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
Gregori-Pla, C
diffuse optics
diffuse correlation spectroscopy
stroke
sleep disorders
title_short Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
title_full Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
title_fullStr Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
title_full_unstemmed Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
title_sort Microvascular cerebral blood flow fluctuations in association with apneas and hypopneas in acute ischemic stroke
dc.creator.none.fl_str_mv Gregori-Pla, C
Delgado-Mederos, R
Cotta, G
Giacalone, G
Maruccia, F
Avtzi, S
Prats-Sanchez, L
Martinez-Domeno, A
Camps-Renom, P
Marti-Fabregas, J
Durduran, T
Mayos, M
author Gregori-Pla, C
author_facet Gregori-Pla, C
Delgado-Mederos, R
Cotta, G
Giacalone, G
Maruccia, F
Avtzi, S
Prats-Sanchez, L
Martinez-Domeno, A
Camps-Renom, P
Marti-Fabregas, J
Durduran, T
Mayos, M
author_role author
author2 Delgado-Mederos, R
Cotta, G
Giacalone, G
Maruccia, F
Avtzi, S
Prats-Sanchez, L
Martinez-Domeno, A
Camps-Renom, P
Marti-Fabregas, J
Durduran, T
Mayos, M
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv diffuse optics
diffuse correlation spectroscopy
stroke
sleep disorders
topic diffuse optics
diffuse correlation spectroscopy
stroke
sleep disorders
description In a pilot study on acute ischemic stroke (AIS) patients, unexpected periodic fluctuations in microvascular cerebral blood flow (CBF) had been observed. Motivated by the relative lack of information about the impact of the emergence of breathing disorders in association with stroke on cerebral hemodynamics, we hypothesized that these fluctuations are due to apneic and hypopneic events. A total of 28 patients were screened within the first week after stroke with a pulse oximeter. Five (18%) showed fluctuations of arterial blood oxygen saturation (>= 3 % ) and were included in the study. Near-infrared diffuse correlation spectroscopy (DCS) was utilized bilaterally to measure the frontal lobe CBF alongside respiratory polygraphy. Biphasic CBF fluctuations were observed with a bilateral increase of 27.1 % +/- 17.7 % and 29.0 % +/- 17.4 % for the ipsilesional and contralesional hemispheres, respectively, and a decrease of -19.3 % +/- 9.1 % and -21.0 % +/- 8.9 % for the ipsilesional and contralesional hemispheres, respectively. The polygraph revealed that, in general, the fluctuations were associated with apneic and hypopneic events. This study motivates us to investigate whether the impact of altered respiratory patterns on cerebral hemodynamics can be detrimental in AIS patients. patients. (C) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2778
http://ddd.uab.cat/record/222720
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2778
http://ddd.uab.cat/record/222720
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
publisher.none.fl_str_mv SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS
dc.source.none.fl_str_mv Neurophotonics
ISSN: 2329423X
ISSNe: 23294248
reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,228081

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