Multiple Myeloma with primary manifestation in the mandible: a case report

Multiple myeloma is a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions in the vertebrae, ribs, pelvic bone, skull and jaw. We report on a clinical case of an 81-year-old male patient who presented with a tumefaction in the mandibular symphysis region, which had evolv...

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Autores: Vieira-Leite Segundo, Airton, Lima Falcão, Marcelo Ferreira, Correia-Lins Filho, Romualdo, Marqués Soares, Maria Sueli, López López, José, 1958-, Chimenos Küstner, Eduardo
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/50740
Acesso em linha:https://hdl.handle.net/2445/50740
Access Level:acceso abierto
Palavra-chave:Càncer
Maxil·lars
Cancer
Jaws
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spelling Multiple Myeloma with primary manifestation in the mandible: a case reportVieira-Leite Segundo, AirtonLima Falcão, Marcelo FerreiraCorreia-Lins Filho, RomualdoMarqués Soares, Maria SueliLópez López, José, 1958-Chimenos Küstner, EduardoCàncerMaxil·larsCancerJawsMultiple myeloma is a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions in the vertebrae, ribs, pelvic bone, skull and jaw. We report on a clinical case of an 81-year-old male patient who presented with a tumefaction in the mandibular symphysis region, which had evolved over the previous seven months. In the radiographic examination, an extensive osteolytic lesion was observed in the region mentioned above. An incisional biopsy was performed and a histopathological study revealed a malignant hematopoietic neoplasm formed by plasmacytoid cells. During the bone gammagraphy a dissemination of the disease was detected in the scapula, clavicle and ribs. The diagnosis was multiple myeloma. Knowledge about the maxillofacial manifestations of multiple myeloma is important for the early diagnosis of the disease, since its primary form can manifest itself in the jaw. In the clinical case presented here, we highlight the interdisciplinarity needed to obtain a diagnosis and treatment of multiple myelomaMedicina Oral SL2008info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/50740Articles publicats en revistes (Odontoestomatologia)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: http://www.medicinaoral.com/Medicina Oral, Patología Oral y Cirugia Bucal, 2008, vol. 13, num. 4, p. 232-234(c) Medicina Oral SL, 2008info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/507402026-05-27T06:46:51Z
dc.title.none.fl_str_mv Multiple Myeloma with primary manifestation in the mandible: a case report
title Multiple Myeloma with primary manifestation in the mandible: a case report
spellingShingle Multiple Myeloma with primary manifestation in the mandible: a case report
Vieira-Leite Segundo, Airton
Càncer
Maxil·lars
Cancer
Jaws
title_short Multiple Myeloma with primary manifestation in the mandible: a case report
title_full Multiple Myeloma with primary manifestation in the mandible: a case report
title_fullStr Multiple Myeloma with primary manifestation in the mandible: a case report
title_full_unstemmed Multiple Myeloma with primary manifestation in the mandible: a case report
title_sort Multiple Myeloma with primary manifestation in the mandible: a case report
dc.creator.none.fl_str_mv Vieira-Leite Segundo, Airton
Lima Falcão, Marcelo Ferreira
Correia-Lins Filho, Romualdo
Marqués Soares, Maria Sueli
López López, José, 1958-
Chimenos Küstner, Eduardo
author Vieira-Leite Segundo, Airton
author_facet Vieira-Leite Segundo, Airton
Lima Falcão, Marcelo Ferreira
Correia-Lins Filho, Romualdo
Marqués Soares, Maria Sueli
López López, José, 1958-
Chimenos Küstner, Eduardo
author_role author
author2 Lima Falcão, Marcelo Ferreira
Correia-Lins Filho, Romualdo
Marqués Soares, Maria Sueli
López López, José, 1958-
Chimenos Küstner, Eduardo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Càncer
Maxil·lars
Cancer
Jaws
topic Càncer
Maxil·lars
Cancer
Jaws
description Multiple myeloma is a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions in the vertebrae, ribs, pelvic bone, skull and jaw. We report on a clinical case of an 81-year-old male patient who presented with a tumefaction in the mandibular symphysis region, which had evolved over the previous seven months. In the radiographic examination, an extensive osteolytic lesion was observed in the region mentioned above. An incisional biopsy was performed and a histopathological study revealed a malignant hematopoietic neoplasm formed by plasmacytoid cells. During the bone gammagraphy a dissemination of the disease was detected in the scapula, clavicle and ribs. The diagnosis was multiple myeloma. Knowledge about the maxillofacial manifestations of multiple myeloma is important for the early diagnosis of the disease, since its primary form can manifest itself in the jaw. In the clinical case presented here, we highlight the interdisciplinarity needed to obtain a diagnosis and treatment of multiple myeloma
publishDate 2008
dc.date.none.fl_str_mv 2008
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/50740
url https://hdl.handle.net/2445/50740
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://www.medicinaoral.com/
Medicina Oral, Patología Oral y Cirugia Bucal, 2008, vol. 13, num. 4, p. 232-234
dc.rights.none.fl_str_mv (c) Medicina Oral SL, 2008
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Medicina Oral SL, 2008
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Medicina Oral SL
publisher.none.fl_str_mv Medicina Oral SL
dc.source.none.fl_str_mv Articles publicats en revistes (Odontoestomatologia)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301629

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