Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints

One of the most prevalent symptoms of post-COVID condition is cognitive impairment, which results in a significant degree of disability and low quality of life. In studies with large sample sizes, attention, memory, and executive function were reported as long-term cognitive symptoms. This study aim...

Descripción completa

Detalles Bibliográficos
Autores: Ariza, Mar, Cano, Neus, Segura Fàbregas, Bàrbara, Adan Puig, Ana, Bargalló Alabart, Núria, Caldú Ferrús, Xavier, Campabadal Delgado, Anna, Jurado Luque, Maria Àngels, Mataro Serrat, Maria, Pueyo Benito, Roser, Sala Llonch, Roser, Barrué Subirana, Cristian|||0000-0002-3342-1085, Béjar Alonso, Javier|||0000-0001-5281-3888, Cortés García, Claudio Ulises|||0000-0003-0192-3096, Junqué Plaja, Carme, Garolera Freixa, Maite
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/383357
Acceso en línea:https://hdl.handle.net/2117/383357
https://dx.doi.org/10.3389/fnagi.2022.1029842
Access Level:acceso abierto
Palabra clave:COVID-19 (Disease)
Neuropsychological tests
COVID-19
Post-COVID-19 condition
NeuroCOVID
Neuropsychological test
Cognitive function
COVID-19 (Malaltia)
Infeccions per coronavirus
Neuropsicologia--Tests
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental::Psicologia
id ES_a997cc6a934a28a843dba04541b3bc07
oai_identifier_str oai:upcommons.upc.edu:2117/383357
network_acronym_str ES
network_name_str España
repository_id_str
spelling Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaintsAriza, MarCano, NeusSegura Fàbregas, BàrbaraAdan Puig, AnaBargalló Alabart, NúriaCaldú Ferrús, XavierCampabadal Delgado, AnnaJurado Luque, Maria ÀngelsMataro Serrat, MariaPueyo Benito, RoserSala Llonch, RoserBarrué Subirana, Cristian|||0000-0002-3342-1085Béjar Alonso, Javier|||0000-0001-5281-3888Cortés García, Claudio Ulises|||0000-0003-0192-3096Junqué Plaja, CarmeGarolera Freixa, MaiteCOVID-19 (Disease)Neuropsychological testsCOVID-19Post-COVID-19 conditionNeuroCOVIDNeuropsychological testCognitive functionCOVID-19 (Malaltia)Infeccions per coronavirusNeuropsicologia--TestsÀrees temàtiques de la UPC::Ciències de la salut::Salut mental::PsicologiaOne of the most prevalent symptoms of post-COVID condition is cognitive impairment, which results in a significant degree of disability and low quality of life. In studies with large sample sizes, attention, memory, and executive function were reported as long-term cognitive symptoms. This study aims to describe cognitive dysfunction in large post-COVID condition individuals, compare objective neuropsychological performance in those post-COVID condition individuals with and without cognitive complaints, and identify short cognitive exams that can differentiate individuals with post-COVID symptoms from controls. To address these aims, the Nautilus project was started in June 2021. During the first year, we collected 428 participants’ data, including 319 post-COVID and 109 healthy controls (18–65 years old) from those who underwent a comprehensive neuropsychological battery for cognitive assessment. Scores on tests assessing global cognition, learning and long-term memory, processing speed, language and executive functions were significantly worse in the post-COVID condition group than in healthy controls. Montreal Cognitive Assessment, digit symbol test, and phonetic verbal fluency were significant in the binomial logistic regression model and could effectively distinguish patients from controls with good overall sensitivity and accuracy. Neuropsychological test results did not differ between those with and without cognitive complaints. Our research suggests that patients with post-COVID conditions experience significant cognitive impairment and that routine tests like the Montreal Cognitive Assessment, digit symbol, and phonetic verbal fluency test might identify cognitive impairment. Thus, the administration of these tests would be helpful for all patients with post-COVID-19 symptoms, regardless of whether cognitive complaints are present or absent.Peer ReviewedNAUTILUS-Project Collaborative GroupFrontiers Media20222022-10-2020232023-02-15journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/383357https://dx.doi.org/10.3389/fnagi.2022.1029842reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/3833572026-05-27T15:37:01Z
dc.title.none.fl_str_mv Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
title Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
spellingShingle Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
Ariza, Mar
COVID-19 (Disease)
Neuropsychological tests
COVID-19
Post-COVID-19 condition
NeuroCOVID
Neuropsychological test
Cognitive function
COVID-19 (Malaltia)
Infeccions per coronavirus
Neuropsicologia--Tests
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental::Psicologia
title_short Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
title_full Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
title_fullStr Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
title_full_unstemmed Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
title_sort Neuropsychological impairment in post-COVID condition individuals with and without cognitive complaints
dc.creator.none.fl_str_mv Ariza, Mar
Cano, Neus
Segura Fàbregas, Bàrbara
Adan Puig, Ana
Bargalló Alabart, Núria
Caldú Ferrús, Xavier
Campabadal Delgado, Anna
Jurado Luque, Maria Àngels
Mataro Serrat, Maria
Pueyo Benito, Roser
Sala Llonch, Roser
Barrué Subirana, Cristian|||0000-0002-3342-1085
Béjar Alonso, Javier|||0000-0001-5281-3888
Cortés García, Claudio Ulises|||0000-0003-0192-3096
Junqué Plaja, Carme
Garolera Freixa, Maite
author Ariza, Mar
author_facet Ariza, Mar
Cano, Neus
Segura Fàbregas, Bàrbara
Adan Puig, Ana
Bargalló Alabart, Núria
Caldú Ferrús, Xavier
Campabadal Delgado, Anna
Jurado Luque, Maria Àngels
Mataro Serrat, Maria
Pueyo Benito, Roser
Sala Llonch, Roser
Barrué Subirana, Cristian|||0000-0002-3342-1085
Béjar Alonso, Javier|||0000-0001-5281-3888
Cortés García, Claudio Ulises|||0000-0003-0192-3096
Junqué Plaja, Carme
Garolera Freixa, Maite
author_role author
author2 Cano, Neus
Segura Fàbregas, Bàrbara
Adan Puig, Ana
Bargalló Alabart, Núria
Caldú Ferrús, Xavier
Campabadal Delgado, Anna
Jurado Luque, Maria Àngels
Mataro Serrat, Maria
Pueyo Benito, Roser
Sala Llonch, Roser
Barrué Subirana, Cristian|||0000-0002-3342-1085
Béjar Alonso, Javier|||0000-0001-5281-3888
Cortés García, Claudio Ulises|||0000-0003-0192-3096
Junqué Plaja, Carme
Garolera Freixa, Maite
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv COVID-19 (Disease)
Neuropsychological tests
COVID-19
Post-COVID-19 condition
NeuroCOVID
Neuropsychological test
Cognitive function
COVID-19 (Malaltia)
Infeccions per coronavirus
Neuropsicologia--Tests
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental::Psicologia
topic COVID-19 (Disease)
Neuropsychological tests
COVID-19
Post-COVID-19 condition
NeuroCOVID
Neuropsychological test
Cognitive function
COVID-19 (Malaltia)
Infeccions per coronavirus
Neuropsicologia--Tests
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental::Psicologia
description One of the most prevalent symptoms of post-COVID condition is cognitive impairment, which results in a significant degree of disability and low quality of life. In studies with large sample sizes, attention, memory, and executive function were reported as long-term cognitive symptoms. This study aims to describe cognitive dysfunction in large post-COVID condition individuals, compare objective neuropsychological performance in those post-COVID condition individuals with and without cognitive complaints, and identify short cognitive exams that can differentiate individuals with post-COVID symptoms from controls. To address these aims, the Nautilus project was started in June 2021. During the first year, we collected 428 participants’ data, including 319 post-COVID and 109 healthy controls (18–65 years old) from those who underwent a comprehensive neuropsychological battery for cognitive assessment. Scores on tests assessing global cognition, learning and long-term memory, processing speed, language and executive functions were significantly worse in the post-COVID condition group than in healthy controls. Montreal Cognitive Assessment, digit symbol test, and phonetic verbal fluency were significant in the binomial logistic regression model and could effectively distinguish patients from controls with good overall sensitivity and accuracy. Neuropsychological test results did not differ between those with and without cognitive complaints. Our research suggests that patients with post-COVID conditions experience significant cognitive impairment and that routine tests like the Montreal Cognitive Assessment, digit symbol, and phonetic verbal fluency test might identify cognitive impairment. Thus, the administration of these tests would be helpful for all patients with post-COVID-19 symptoms, regardless of whether cognitive complaints are present or absent.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-10-20
2023
2023-02-15
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/383357
https://dx.doi.org/10.3389/fnagi.2022.1029842
url https://hdl.handle.net/2117/383357
https://dx.doi.org/10.3389/fnagi.2022.1029842
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869416034956476416
score 15,228081

Similares en LA Referencia