Hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) determination of cocaine and its metabolites benzoylecgonine, ecgonine methyl ester, and cocaethylene in hair samples

This study reports the development and validation of a method using hydrophilic interaction liquid chromatography–tandem mass spectrometry (HILIC-MS/MS) for the analysis of cocaine and its metabolites benzoylecgonine (BE), ecgonine methyl ester (EME), and cocaethylene (CE) in hair samples.

Detalhes bibliográficos
Autores: Quintela, Óscar, Lendoiro Belío, Elena, Cruz Landeira, Angelines, Castro Ríos, Ana de, Quevedo, Alfredo, Jurado, Carmen, López-Rivadulla Lamas, Manuel
Tipo de documento: artigo
Data de publicação:2010
País:España
Recursos:Universidad de Santiago de Compostela (USC)
Repositório:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglês
OAI Identifier:oai:minerva.usc.gal:10347/38674
Acesso em linha:https://hdl.handle.net/10347/38674
Access Level:Acceso aberto
Palavra-chave:Hydrophilic interaction liquid chromatography–tandem mass spectrometry (HILIC-MS/MS)
Cocaine and metabolites
Ecgonine methyl ester
Hair analysis
3214 Toxicología
Descrição
Resumo:This study reports the development and validation of a method using hydrophilic interaction liquid chromatography–tandem mass spectrometry (HILIC-MS/MS) for the analysis of cocaine and its metabolites benzoylecgonine (BE), ecgonine methyl ester (EME), and cocaethylene (CE) in hair samples.

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