Image_4_Performance of spectral flow cytometry and mass cytometry for the study of innate myeloid cell populations.tif [Dataset]

[Introduction]: Monitoring of innate myeloid cells (IMC) is broadly applied in basic and translational research, as well as in diagnostic patient care. Due to their immunophenotypic heterogeneity and biological plasticity, analysis of IMC populations typically requires large panels of markers. Curre...

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Detalhes bibliográficos
Autores: Pan, Kyra van der, Khatri, Indu, Jager, Anniek L. de, Louis, Alesha, Kassem, Sara, Naber, Brigitta A. E., Laat, Inge F. de, Hameetman, Marjolijn, Comans, Suzanne, Orfao, Alberto, Dongen, J. J. M. van, Díez, Paula, Teodosio, Cristina
Formato: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/360961
Acesso em linha:http://hdl.handle.net/10261/360961
Access Level:acceso abierto
Palavra-chave:Spectral flow cytometry
Myeloid cells
Immunophenotyping
cyTOF
Mass cytometry
Descrição
Resumo:[Introduction]: Monitoring of innate myeloid cells (IMC) is broadly applied in basic and translational research, as well as in diagnostic patient care. Due to their immunophenotypic heterogeneity and biological plasticity, analysis of IMC populations typically requires large panels of markers. Currently, two cytometry-based techniques allow for the simultaneous detection of ≥40 markers: spectral flow cytometry (SFC) and mass cytometry (MC). However, little is known about the comparability of SFC and MC in studying IMC populations.

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