Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing

Purpose: This study aims to assess inappropriate prescribing (IP) to elderly patients during the month prior to hospitalization and to compare different IP criteria. Methods: An observational, prospective and multicentric study was carried out in the internal medicine services of seven Spanish hospi...

Full description

Bibliographic Details
Authors: San-Jose, A, Agusti, A, Vidal, X, Formiga, F, Lopez-Soto, A, Fernandez-Moyano, A, Garcia, J, Ramirez-Duque, N, Torres, OH, Barbe, J
Format: article
Status:Published version
Publication Date:2014
Country:España
Institution:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repository:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p8836
Online Access:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8836
http://hdl.handle.net/2445/68493
Access Level:Open access
Keyword:Polypharmacy
Older multimorbidity patients
Inappropriate prescribing
Potentially inappropriate medicines
Potentially Prescribing Omissions
id ES_9fcc46ad38667da6db9612f8b3c0f9f8
oai_identifier_str oai:iibsantpau.fundanetsuite.com:p8836
network_acronym_str ES
network_name_str España
repository_id_str
spelling Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribingSan-Jose, AAgusti, AVidal, XFormiga, FLopez-Soto, AFernandez-Moyano, AGarcia, JRamirez-Duque, NTorres, OHBarbe, JPolypharmacyOlder multimorbidity patientsInappropriate prescribingPotentially inappropriate medicinesPotentially Prescribing OmissionsPurpose: This study aims to assess inappropriate prescribing (IP) to elderly patients during the month prior to hospitalization and to compare different IP criteria. Methods: An observational, prospective and multicentric study was carried out in the internal medicine services of seven Spanish hospitals. Patients aged 75 years and olderwere randomly selected after hospital admission for a year. To assess potentially inappropriate medicines (PIMs), the Beers and STOPP criteria were used and to assess potentially prescribing omissions (PPOs), the START criteria and ACOVE-3 medicine quality indicators were used. An analysis to assess factors associated with IP was performed. Results: 672 patients [median age (Q1-Q3) 82 (79-86) years, 55.9% female] were included. Median prescribed medicines in the month prior to hospitalization were 10(Q1-Q3 7-13). The prevalence of IP was 87.6%, and 54.3% of patients had PIMs and PPOs concurrently. A higher prevalence rate of PIMs was predicted using the STOPP criteria than with the Beers criteria (p < 0.001) and a higher prevalence of PPOs using the ACOVE-3 criteria than using the START criteria (p < 0.001) was observed. Polypharmacy (>= 10 medicines) was the strongest predictor of IP [OR = 11.34 95% confidence interval (CI) 4.96-25.94], PIMs [OR = 14.16, 95% CI 6.44-31.12], Beers-listed PIMs [OR = 8.19, 95% CI 3.01-22.28] and STOPP-listed PIMs [OR = 8.21, 95% CI 3.47-19.44]. PIMs was the strongest predictor of PPOs [OR = 2.79, 95% CI 1.81-4.28]. Conclusions: A high prevalence of polypharmacy and PIMs and PPOs were reported. More than half the patients had simultaneous PIMs and PPOs. The related factors to PIMs and PPOs were different. (c) 2014 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.ELSEVIER2014info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8836http://hdl.handle.net/2445/68493European Journal of Internal MedicineISSN: 09536205ISSNe: 18790828reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauinstname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)Inglésinfo:eu-repo/semantics/openAccessoai:iibsantpau.fundanetsuite.com:p88362026-06-14T12:41:47Z
dc.title.none.fl_str_mv Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
title Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
spellingShingle Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
San-Jose, A
Polypharmacy
Older multimorbidity patients
Inappropriate prescribing
Potentially inappropriate medicines
Potentially Prescribing Omissions
title_short Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
title_full Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
title_fullStr Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
title_full_unstemmed Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
title_sort Inappropriate prescribing to older patients admitted to hospital: A comparison of different tools of misprescribing and underprescribing
dc.creator.none.fl_str_mv San-Jose, A
Agusti, A
Vidal, X
Formiga, F
Lopez-Soto, A
Fernandez-Moyano, A
Garcia, J
Ramirez-Duque, N
Torres, OH
Barbe, J
author San-Jose, A
author_facet San-Jose, A
Agusti, A
Vidal, X
Formiga, F
Lopez-Soto, A
Fernandez-Moyano, A
Garcia, J
Ramirez-Duque, N
Torres, OH
Barbe, J
author_role author
author2 Agusti, A
Vidal, X
Formiga, F
Lopez-Soto, A
Fernandez-Moyano, A
Garcia, J
Ramirez-Duque, N
Torres, OH
Barbe, J
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Polypharmacy
Older multimorbidity patients
Inappropriate prescribing
Potentially inappropriate medicines
Potentially Prescribing Omissions
topic Polypharmacy
Older multimorbidity patients
Inappropriate prescribing
Potentially inappropriate medicines
Potentially Prescribing Omissions
description Purpose: This study aims to assess inappropriate prescribing (IP) to elderly patients during the month prior to hospitalization and to compare different IP criteria. Methods: An observational, prospective and multicentric study was carried out in the internal medicine services of seven Spanish hospitals. Patients aged 75 years and olderwere randomly selected after hospital admission for a year. To assess potentially inappropriate medicines (PIMs), the Beers and STOPP criteria were used and to assess potentially prescribing omissions (PPOs), the START criteria and ACOVE-3 medicine quality indicators were used. An analysis to assess factors associated with IP was performed. Results: 672 patients [median age (Q1-Q3) 82 (79-86) years, 55.9% female] were included. Median prescribed medicines in the month prior to hospitalization were 10(Q1-Q3 7-13). The prevalence of IP was 87.6%, and 54.3% of patients had PIMs and PPOs concurrently. A higher prevalence rate of PIMs was predicted using the STOPP criteria than with the Beers criteria (p < 0.001) and a higher prevalence of PPOs using the ACOVE-3 criteria than using the START criteria (p < 0.001) was observed. Polypharmacy (>= 10 medicines) was the strongest predictor of IP [OR = 11.34 95% confidence interval (CI) 4.96-25.94], PIMs [OR = 14.16, 95% CI 6.44-31.12], Beers-listed PIMs [OR = 8.19, 95% CI 3.01-22.28] and STOPP-listed PIMs [OR = 8.21, 95% CI 3.47-19.44]. PIMs was the strongest predictor of PPOs [OR = 2.79, 95% CI 1.81-4.28]. Conclusions: A high prevalence of polypharmacy and PIMs and PPOs were reported. More than half the patients had simultaneous PIMs and PPOs. The related factors to PIMs and PPOs were different. (c) 2014 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
publishDate 2014
dc.date.none.fl_str_mv 2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8836
http://hdl.handle.net/2445/68493
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8836
http://hdl.handle.net/2445/68493
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ELSEVIER
publisher.none.fl_str_mv ELSEVIER
dc.source.none.fl_str_mv European Journal of Internal Medicine
ISSN: 09536205
ISSNe: 18790828
reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869414958363574272
score 15,198674

Similar Items