Active transcription without histone modifications
Gene expression is regulated by proteins such as transcription factors, as well as by chromatin modifications on DNA and histones. Some histone modifications have been associated to transcriptional activation (i.e. H3K4me1, H3K4me3, H3K9ac, H3K27ac or H3K36me3) whereas others with gene silencing (H3...
| Autores: | , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:10230/26186 |
| Acceso en línea: | http://hdl.handle.net/10230/26186 http://dx.doi.org/10.18632/oncotarget.6437 |
| Access Level: | acceso abierto |
| Palabra clave: | Drosòfila Epigènesi Chromosome Section Drosophila Development Epigenetics Transcription |
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Active transcription without histone modificationsPérez-Lluch, SílviaGuigó Serra, RodericCorominas Guiu, MontserratDrosòfilaEpigènesiChromosome SectionDrosophilaDevelopmentEpigeneticsTranscriptionGene expression is regulated by proteins such as transcription factors, as well as by chromatin modifications on DNA and histones. Some histone modifications have been associated to transcriptional activation (i.e. H3K4me1, H3K4me3, H3K9ac, H3K27ac or H3K36me3) whereas others with gene silencing (H3K9me3 and H3K27me3). However, and challenging this premise, we have identified a set of genes in Drosophila melanogaster that are actively expressed in the absence of the canonical histone marks.Impact Journals201620162015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/26186http://dx.doi.org/10.18632/oncotarget.6437reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésOncotarget. 2015;6(39):41401Published originally by Impact Journals at http://dx.doi.org/10.18632/oncotarget.6437 under a Creative Commons Attribution 3.0 License.http://creativecommons.org/licenses/by/3.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/261862026-05-29T05:05:01Z |
| dc.title.none.fl_str_mv |
Active transcription without histone modifications |
| title |
Active transcription without histone modifications |
| spellingShingle |
Active transcription without histone modifications Pérez-Lluch, Sílvia Drosòfila Epigènesi Chromosome Section Drosophila Development Epigenetics Transcription |
| title_short |
Active transcription without histone modifications |
| title_full |
Active transcription without histone modifications |
| title_fullStr |
Active transcription without histone modifications |
| title_full_unstemmed |
Active transcription without histone modifications |
| title_sort |
Active transcription without histone modifications |
| dc.creator.none.fl_str_mv |
Pérez-Lluch, Sílvia Guigó Serra, Roderic Corominas Guiu, Montserrat |
| author |
Pérez-Lluch, Sílvia |
| author_facet |
Pérez-Lluch, Sílvia Guigó Serra, Roderic Corominas Guiu, Montserrat |
| author_role |
author |
| author2 |
Guigó Serra, Roderic Corominas Guiu, Montserrat |
| author2_role |
author author |
| dc.subject.none.fl_str_mv |
Drosòfila Epigènesi Chromosome Section Drosophila Development Epigenetics Transcription |
| topic |
Drosòfila Epigènesi Chromosome Section Drosophila Development Epigenetics Transcription |
| description |
Gene expression is regulated by proteins such as transcription factors, as well as by chromatin modifications on DNA and histones. Some histone modifications have been associated to transcriptional activation (i.e. H3K4me1, H3K4me3, H3K9ac, H3K27ac or H3K36me3) whereas others with gene silencing (H3K9me3 and H3K27me3). However, and challenging this premise, we have identified a set of genes in Drosophila melanogaster that are actively expressed in the absence of the canonical histone marks. |
| publishDate |
2015 |
| dc.date.none.fl_str_mv |
2015 2016 2016 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10230/26186 http://dx.doi.org/10.18632/oncotarget.6437 |
| url |
http://hdl.handle.net/10230/26186 http://dx.doi.org/10.18632/oncotarget.6437 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Oncotarget. 2015;6(39):41401 |
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http://creativecommons.org/licenses/by/3.0/ info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by/3.0/ |
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openAccess |
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application/pdf application/pdf |
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Impact Journals |
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Impact Journals |
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reponame:Recercat. Dipósit de la Recerca de Catalunya instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
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Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
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Recercat. Dipósit de la Recerca de Catalunya |
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Recercat. Dipósit de la Recerca de Catalunya |
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15.228081 |