DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS naïve HIV-infected patients: a retrospective study.

Most of the circulating Vitamin D (VitD) is transported bound to vitamin D-binding protein (DBP), and several DBP single nucleotide polymorphisms (SNPs) have been related to circulating VitD concentration and disease. In this study, we evaluated the association among DBP SNPs and AIDS progression in...

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Detalhes bibliográficos
Autores: Jimenez-Sousa, MA, Jimenez, JL, Fernandez-Rodriguez, A, Bellon, JM, Rodriguez, C, Riera, M, Portilla, J, Castro, A, Munoz-Fernandez, MA, Resino, S
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2019
País:España
Recursos:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
Repositório:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
OAI Identifier:oai:isabial.fundanetsuite.com:p5453
Acesso em linha:https://isabial.portalinvestigacion.com/publicaciones5453
Access Level:Acceso aberto
Palavra-chave:AIDS, DBP, LTNPs, Non-progression, Single nucleotide polymorphisms
Descrição
Resumo:Most of the circulating Vitamin D (VitD) is transported bound to vitamin D-binding protein (DBP), and several DBP single nucleotide polymorphisms (SNPs) have been related to circulating VitD concentration and disease. In this study, we evaluated the association among DBP SNPs and AIDS progression in antiretroviral treatment (ART)-naïve-HIV-infected patients.