Synthesis of degradable cationic carbosilane dendrimers based on Si-O or ester bonds
Several cationic carbosilane dendrimers have been synthesized containing two different types of degradable bonds: SieO and ester bonds. The first type of systems was prepared by reacting carbosilane dendrimers containing peripheral SieCl bonds with first generation dendrons presenting a eOH function...
| Autores: | , , , , |
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| Tipo de documento: | artigo |
| Data de publicação: | 2016 |
| País: | España |
| Recursos: | Universidad de Alcalá (UAH) |
| Repositório: | e_Buah Biblioteca Digital Universidad de Alcalá |
| Idioma: | inglês |
| OAI Identifier: | oai:ebuah.uah.es:10017/34059 |
| Acesso em linha: | http://hdl.handle.net/10017/34059 https://dx.doi.org/10.1016/j.tet.2016.07.084 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Biodegradable dendrimers Carbosilane dendrimers Ester bonds Stability Química Chemistry |
| Resumo: | Several cationic carbosilane dendrimers have been synthesized containing two different types of degradable bonds: SieO and ester bonds. The first type of systems was prepared by reacting carbosilane dendrimers containing peripheral SieCl bonds with first generation dendrons presenting a eOH function at the focal point and amine peripheral functions. The second type of systems was prepared by esterification between a dendrimer containing acid groups and an alcoholamine. The stability in water of both types of cationic systems was evaluated |
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