Spatiotemporal whole-brain activity and functional connectivity of melodies recognition

Music is a non-verbal human language, built on logical, hierarchical structures, that offers excellent opportunities to explore how the brain processes complex spatiotemporal auditory sequences. Using the high temporal resolution of magnetoencephalography, we investigated the unfolding brain dynamic...

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Autores: Bonetti, Leonardo, Brattico, Elvira, Carlomagno, Francesco, Cabral, Joana, Stevner, Angus, Deco, Gustavo, Whybrow, Peter C., Pearce, Marcus, Pantazis, Dimitrios, Vuust, Peter, Kringelbach, Morten L.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/70433
Acceso en línea:http://hdl.handle.net/10230/70433
http://dx.doi.org/10.1093/cercor/bhae320
Access Level:acceso abierto
Palabra clave:Memory
Sequence recognition
Brain spatiotemporal dynamics
Functional connectivity
Magnetoencephalography (MEG)
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network_name_str España
repository_id_str
dc.title.none.fl_str_mv Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
title Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
spellingShingle Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
Bonetti, Leonardo
Memory
Sequence recognition
Brain spatiotemporal dynamics
Functional connectivity
Magnetoencephalography (MEG)
title_short Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
title_full Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
title_fullStr Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
title_full_unstemmed Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
title_sort Spatiotemporal whole-brain activity and functional connectivity of melodies recognition
dc.creator.none.fl_str_mv Bonetti, Leonardo
Brattico, Elvira
Carlomagno, Francesco
Cabral, Joana
Stevner, Angus
Deco, Gustavo
Whybrow, Peter C.
Pearce, Marcus
Pantazis, Dimitrios
Vuust, Peter
Kringelbach, Morten L.
author Bonetti, Leonardo
author_facet Bonetti, Leonardo
Brattico, Elvira
Carlomagno, Francesco
Cabral, Joana
Stevner, Angus
Deco, Gustavo
Whybrow, Peter C.
Pearce, Marcus
Pantazis, Dimitrios
Vuust, Peter
Kringelbach, Morten L.
author_role author
author2 Brattico, Elvira
Carlomagno, Francesco
Cabral, Joana
Stevner, Angus
Deco, Gustavo
Whybrow, Peter C.
Pearce, Marcus
Pantazis, Dimitrios
Vuust, Peter
Kringelbach, Morten L.
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Memory
Sequence recognition
Brain spatiotemporal dynamics
Functional connectivity
Magnetoencephalography (MEG)
topic Memory
Sequence recognition
Brain spatiotemporal dynamics
Functional connectivity
Magnetoencephalography (MEG)
description Music is a non-verbal human language, built on logical, hierarchical structures, that offers excellent opportunities to explore how the brain processes complex spatiotemporal auditory sequences. Using the high temporal resolution of magnetoencephalography, we investigated the unfolding brain dynamics of 70 participants during the recognition of previously memorized musical sequences compared to novel sequences matched in terms of entropy and information content. Measures of both whole-brain activity and functional connectivity revealed a widespread brain network underlying the recognition of the memorized auditory sequences, which comprised primary auditory cortex, superior temporal gyrus, insula, frontal operculum, cingulate gyrus, orbitofrontal cortex, basal ganglia, thalamus, and hippocampus. Furthermore, while the auditory cortex responded mainly to the first tones of the sequences, the activity of higher-order brain areas such as the cingulate gyrus, frontal operculum, hippocampus, and orbitofrontal cortex largely increased over time during the recognition of the memorized versus novel musical sequences. In conclusion, using a wide range of analytical techniques spanning from decoding to functional connectivity and building on previous works, our study provided new insights into the spatiotemporal whole-brain mechanisms for conscious recognition of auditory sequences.
publishDate 2024
dc.date.none.fl_str_mv 2024
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/70433
http://dx.doi.org/10.1093/cercor/bhae320
http://hdl.handle.net/10230/70433
url http://hdl.handle.net/10230/70433
http://dx.doi.org/10.1093/cercor/bhae320
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Cerebral Cortex. 2024 Aug;34(8):bhae320
info:eu-repo/grantAgreement/EC/H2020/720270
info:eu-repo/grantAgreement/EC/H2020/785907
info:eu-repo/grantAgreement/ES/1PE/PSI2016-75688-P
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
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spelling Spatiotemporal whole-brain activity and functional connectivity of melodies recognitionBonetti, LeonardoBrattico, ElviraCarlomagno, FrancescoCabral, JoanaStevner, AngusDeco, GustavoWhybrow, Peter C.Pearce, MarcusPantazis, DimitriosVuust, PeterKringelbach, Morten L.MemorySequence recognitionBrain spatiotemporal dynamicsFunctional connectivityMagnetoencephalography (MEG)Music is a non-verbal human language, built on logical, hierarchical structures, that offers excellent opportunities to explore how the brain processes complex spatiotemporal auditory sequences. Using the high temporal resolution of magnetoencephalography, we investigated the unfolding brain dynamics of 70 participants during the recognition of previously memorized musical sequences compared to novel sequences matched in terms of entropy and information content. Measures of both whole-brain activity and functional connectivity revealed a widespread brain network underlying the recognition of the memorized auditory sequences, which comprised primary auditory cortex, superior temporal gyrus, insula, frontal operculum, cingulate gyrus, orbitofrontal cortex, basal ganglia, thalamus, and hippocampus. Furthermore, while the auditory cortex responded mainly to the first tones of the sequences, the activity of higher-order brain areas such as the cingulate gyrus, frontal operculum, hippocampus, and orbitofrontal cortex largely increased over time during the recognition of the memorized versus novel musical sequences. In conclusion, using a wide range of analytical techniques spanning from decoding to functional connectivity and building on previous works, our study provided new insights into the spatiotemporal whole-brain mechanisms for conscious recognition of auditory sequences.The Center for Music in the Brain (MIB) is funded by the Danish National Research Foundation (project number DNRF117). L.B. is supported by Lundbeck Foundation (Talent Prize 2022), Carlsberg Foundation (CF20-0239), Center for Music in the Brain, Linacre College of the University of Oxford, and Society for Education and Music Psychology (SEMPRE’s 50th Anniversary Awards Scheme). M.L.K. is supported by Center for Music in the Brain, funded by the Danish National Research Foundation (DNRF117), and Centre for Eudaimonia and Human Flourishing funded by the Pettit and Carlsberg Foundations. G.D. is supported by the Spanish Research Project PSI2016-75688-P (AEI/FEDER, EU), by the European Union’s Horizon 2020 Research and Innovation Programme under grant agreements n. 720270 (HBP SGA1) and n. 785907 (HBP SGA2), and by the Catalan AGAUR Programme 2017 SGR 1545. J. C. is supported by La Caixa Foundation, Spain (LCF/BQ/PR22/11920014) and the Foundation for Science and Technology, Portugal (UIDB/50026/2020, UIDP/50026/2020). Additionally, we thank the Italian section of Mensa: The International High IQ Society for the economic support provided to the author Francesco Carlomagno and the University of Bologna for the economic support provided to the students Giulia Donati, Riccardo Proietti, and Giulio Carraturo.Oxford University Press202520252024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/70433http://dx.doi.org/10.1093/cercor/bhae320http://hdl.handle.net/10230/70433reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésCerebral Cortex. 2024 Aug;34(8):bhae320info:eu-repo/grantAgreement/EC/H2020/720270info:eu-repo/grantAgreement/EC/H2020/785907info:eu-repo/grantAgreement/ES/1PE/PSI2016-75688-P© The Author(s) 2024. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/704332026-05-29T05:05:01Z
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