Sex dimorphism in the myocardial response to aortic stenosis

Treibel, T.A. (Thomas A.)|||/items/07a51ca9-29c4-42e6-856e-db9593c33fd4; Kozor, R. (Rebecca)|||/items/6ecbcd45-bfa1-4942-9d89-f47001ddcb77; Fontana, M. (Marianna)|||/items/c282fcc9-f89e-476a-b5a4-87b3f6e3849a; Torlasco, C. (Camilla)|||/items/5ff3c6e8-db04-4990-8393-d32d0d313f4a; Reant, P. (Patricia)|||/items/0b1930f8-0161-46bd-8f52-b1eb409e2b04; Badiani, S. (Sveeta)|||/items/a796a360-47a6-4c38-82a1-7744ddecb508; Espinoza, M. (Maria)|||/items/1ede50e2-e33e-43d9-bbd4-a906d25590ad; Yap, J. (John)|||/items/2a75d28e-7ade-44ee-8752-9128b5044bd0; Diez, J. (Javier)|||/items/adeda0be-cebc-4240-899c-ab26f05dea9c; Hughes, A.D. (Alun D.)|||/items/056a18d3-dc34-4092-a250-ec7298d65a23; Lloyd, G. (Guy)|||/items/a25f3969-46d5-41f7-a4ef-cc980052053c; Moon, J.C. (James C.)|||/items/7c39855a-3b38-428d-b08e-379caa124ea3

Sex dimorphism in the myocardial response to aortic stenosis

Objectives: The goal of this study was to explore sex differences in myocardial remodeling in aortic stenosis (AS) by using echocardiography, cardiac magnetic resonance (CMR), and biomarkers. Background: AS is a disease of both valve and left ventricle (LV). Sex differences in LV remodeling are repo...

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Autores:	Treibel, T.A. (Thomas A.)\|\|\|/items/07a51ca9-29c4-42e6-856e-db9593c33fd4, Kozor, R. (Rebecca)\|\|\|/items/6ecbcd45-bfa1-4942-9d89-f47001ddcb77, Fontana, M. (Marianna)\|\|\|/items/c282fcc9-f89e-476a-b5a4-87b3f6e3849a, Torlasco, C. (Camilla)\|\|\|/items/5ff3c6e8-db04-4990-8393-d32d0d313f4a, Reant, P. (Patricia)\|\|\|/items/0b1930f8-0161-46bd-8f52-b1eb409e2b04, Badiani, S. (Sveeta)\|\|\|/items/a796a360-47a6-4c38-82a1-7744ddecb508, Espinoza, M. (Maria)\|\|\|/items/1ede50e2-e33e-43d9-bbd4-a906d25590ad, Yap, J. (John)\|\|\|/items/2a75d28e-7ade-44ee-8752-9128b5044bd0, Diez, J. (Javier)\|\|\|/items/adeda0be-cebc-4240-899c-ab26f05dea9c, Hughes, A.D. (Alun D.)\|\|\|/items/056a18d3-dc34-4092-a250-ec7298d65a23, Lloyd, G. (Guy)\|\|\|/items/a25f3969-46d5-41f7-a4ef-cc980052053c, Moon, J.C. (James C.)\|\|\|/items/7c39855a-3b38-428d-b08e-379caa124ea3
Tipo de recurso:	artículo
Fecha de publicación:	2018
País:	España
Institución:	Universidad de Navarra
Repositorio:	Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:	inglés
OAI Identifier:	oai:dadun.unav.edu:10171/65821
Acceso en línea:	https://hdl.handle.net/10171/65821
Access Level:	acceso abierto
Palabra clave:	Aortic stenosis Fibrosis Ventricular hypertrophy

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spelling	Sex dimorphism in the myocardial response to aortic stenosisTreibel, T.A. (Thomas A.)\|\|\|/items/07a51ca9-29c4-42e6-856e-db9593c33fd4Kozor, R. (Rebecca)\|\|\|/items/6ecbcd45-bfa1-4942-9d89-f47001ddcb77Fontana, M. (Marianna)\|\|\|/items/c282fcc9-f89e-476a-b5a4-87b3f6e3849aTorlasco, C. (Camilla)\|\|\|/items/5ff3c6e8-db04-4990-8393-d32d0d313f4aReant, P. (Patricia)\|\|\|/items/0b1930f8-0161-46bd-8f52-b1eb409e2b04Badiani, S. (Sveeta)\|\|\|/items/a796a360-47a6-4c38-82a1-7744ddecb508Espinoza, M. (Maria)\|\|\|/items/1ede50e2-e33e-43d9-bbd4-a906d25590adYap, J. (John)\|\|\|/items/2a75d28e-7ade-44ee-8752-9128b5044bd0Diez, J. (Javier)\|\|\|/items/adeda0be-cebc-4240-899c-ab26f05dea9cHughes, A.D. (Alun D.)\|\|\|/items/056a18d3-dc34-4092-a250-ec7298d65a23Lloyd, G. (Guy)\|\|\|/items/a25f3969-46d5-41f7-a4ef-cc980052053cMoon, J.C. (James C.)\|\|\|/items/7c39855a-3b38-428d-b08e-379caa124ea3Aortic stenosisFibrosisVentricular hypertrophyObjectives: The goal of this study was to explore sex differences in myocardial remodeling in aortic stenosis (AS) by using echocardiography, cardiac magnetic resonance (CMR), and biomarkers. Background: AS is a disease of both valve and left ventricle (LV). Sex differences in LV remodeling are reported in AS and may play a role in disease phenotyping. Methods: This study was a prospective assessment of patients awaiting surgical valve replacement for severe AS using echocardiography, the 6-min walking test, biomarkers (high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide), and CMR with late gadolinium enhancement and extracellular volume fraction, which dichotomizes the myocardium into matrix and cell volumes. LV remodeling was categorized into normal geometry, concentric remodeling, concentric hypertrophy, and eccentric hypertrophy.ElsevierDadun. Depósito Académico Digital Universidad de Navarra20232023-03-3020182018-01-0120182018-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/65821reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/658212026-06-21T12:47:57Z
dc.title.none.fl_str_mv	Sex dimorphism in the myocardial response to aortic stenosis
title	Sex dimorphism in the myocardial response to aortic stenosis
spellingShingle	Sex dimorphism in the myocardial response to aortic stenosis Treibel, T.A. (Thomas A.)\|\|\|/items/07a51ca9-29c4-42e6-856e-db9593c33fd4 Aortic stenosis Fibrosis Ventricular hypertrophy
title_short	Sex dimorphism in the myocardial response to aortic stenosis
title_full	Sex dimorphism in the myocardial response to aortic stenosis
title_fullStr	Sex dimorphism in the myocardial response to aortic stenosis
title_full_unstemmed	Sex dimorphism in the myocardial response to aortic stenosis
title_sort	Sex dimorphism in the myocardial response to aortic stenosis
dc.creator.none.fl_str_mv	Treibel, T.A. (Thomas A.)\|\|\|/items/07a51ca9-29c4-42e6-856e-db9593c33fd4 Kozor, R. (Rebecca)\|\|\|/items/6ecbcd45-bfa1-4942-9d89-f47001ddcb77 Fontana, M. (Marianna)\|\|\|/items/c282fcc9-f89e-476a-b5a4-87b3f6e3849a Torlasco, C. (Camilla)\|\|\|/items/5ff3c6e8-db04-4990-8393-d32d0d313f4a Reant, P. (Patricia)\|\|\|/items/0b1930f8-0161-46bd-8f52-b1eb409e2b04 Badiani, S. (Sveeta)\|\|\|/items/a796a360-47a6-4c38-82a1-7744ddecb508 Espinoza, M. (Maria)\|\|\|/items/1ede50e2-e33e-43d9-bbd4-a906d25590ad Yap, J. (John)\|\|\|/items/2a75d28e-7ade-44ee-8752-9128b5044bd0 Diez, J. (Javier)\|\|\|/items/adeda0be-cebc-4240-899c-ab26f05dea9c Hughes, A.D. (Alun D.)\|\|\|/items/056a18d3-dc34-4092-a250-ec7298d65a23 Lloyd, G. (Guy)\|\|\|/items/a25f3969-46d5-41f7-a4ef-cc980052053c Moon, J.C. (James C.)\|\|\|/items/7c39855a-3b38-428d-b08e-379caa124ea3
author	Treibel, T.A. (Thomas A.)\|\|\|/items/07a51ca9-29c4-42e6-856e-db9593c33fd4
author_facet	Treibel, T.A. (Thomas A.)\|\|\|/items/07a51ca9-29c4-42e6-856e-db9593c33fd4 Kozor, R. (Rebecca)\|\|\|/items/6ecbcd45-bfa1-4942-9d89-f47001ddcb77 Fontana, M. (Marianna)\|\|\|/items/c282fcc9-f89e-476a-b5a4-87b3f6e3849a Torlasco, C. (Camilla)\|\|\|/items/5ff3c6e8-db04-4990-8393-d32d0d313f4a Reant, P. (Patricia)\|\|\|/items/0b1930f8-0161-46bd-8f52-b1eb409e2b04 Badiani, S. (Sveeta)\|\|\|/items/a796a360-47a6-4c38-82a1-7744ddecb508 Espinoza, M. (Maria)\|\|\|/items/1ede50e2-e33e-43d9-bbd4-a906d25590ad Yap, J. (John)\|\|\|/items/2a75d28e-7ade-44ee-8752-9128b5044bd0 Diez, J. (Javier)\|\|\|/items/adeda0be-cebc-4240-899c-ab26f05dea9c Hughes, A.D. (Alun D.)\|\|\|/items/056a18d3-dc34-4092-a250-ec7298d65a23 Lloyd, G. (Guy)\|\|\|/items/a25f3969-46d5-41f7-a4ef-cc980052053c Moon, J.C. (James C.)\|\|\|/items/7c39855a-3b38-428d-b08e-379caa124ea3
author_role	author
author2	Kozor, R. (Rebecca)\|\|\|/items/6ecbcd45-bfa1-4942-9d89-f47001ddcb77 Fontana, M. (Marianna)\|\|\|/items/c282fcc9-f89e-476a-b5a4-87b3f6e3849a Torlasco, C. (Camilla)\|\|\|/items/5ff3c6e8-db04-4990-8393-d32d0d313f4a Reant, P. (Patricia)\|\|\|/items/0b1930f8-0161-46bd-8f52-b1eb409e2b04 Badiani, S. (Sveeta)\|\|\|/items/a796a360-47a6-4c38-82a1-7744ddecb508 Espinoza, M. (Maria)\|\|\|/items/1ede50e2-e33e-43d9-bbd4-a906d25590ad Yap, J. (John)\|\|\|/items/2a75d28e-7ade-44ee-8752-9128b5044bd0 Diez, J. (Javier)\|\|\|/items/adeda0be-cebc-4240-899c-ab26f05dea9c Hughes, A.D. (Alun D.)\|\|\|/items/056a18d3-dc34-4092-a250-ec7298d65a23 Lloyd, G. (Guy)\|\|\|/items/a25f3969-46d5-41f7-a4ef-cc980052053c Moon, J.C. (James C.)\|\|\|/items/7c39855a-3b38-428d-b08e-379caa124ea3
author2_role	author author author author author author author author author author author
dc.contributor.none.fl_str_mv	Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv	Aortic stenosis Fibrosis Ventricular hypertrophy
topic	Aortic stenosis Fibrosis Ventricular hypertrophy
description	Objectives: The goal of this study was to explore sex differences in myocardial remodeling in aortic stenosis (AS) by using echocardiography, cardiac magnetic resonance (CMR), and biomarkers. Background: AS is a disease of both valve and left ventricle (LV). Sex differences in LV remodeling are reported in AS and may play a role in disease phenotyping. Methods: This study was a prospective assessment of patients awaiting surgical valve replacement for severe AS using echocardiography, the 6-min walking test, biomarkers (high-sensitivity troponin T and N-terminal pro-brain natriuretic peptide), and CMR with late gadolinium enhancement and extracellular volume fraction, which dichotomizes the myocardium into matrix and cell volumes. LV remodeling was categorized into normal geometry, concentric remodeling, concentric hypertrophy, and eccentric hypertrophy.
publishDate	2018
dc.date.none.fl_str_mv	2018 2018-01-01 2018 2018-01-01 2023 2023-03-30
dc.type.none.fl_str_mv	journal article http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv	info:eu-repo/semantics/article
format	article
dc.identifier.none.fl_str_mv	https://hdl.handle.net/10171/65821
url	https://hdl.handle.net/10171/65821
dc.language.none.fl_str_mv	Inglés eng
language_invalid_str_mv	Inglés
language	eng
dc.rights.none.fl_str_mv	open access http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	open access http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.publisher.none.fl_str_mv	Elsevier
publisher.none.fl_str_mv	Elsevier
dc.source.none.fl_str_mv	reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra instname:Universidad de Navarra
instname_str	Universidad de Navarra
reponame_str	Dadun. Depósito Académico Digital de la Universidad de Navarra
collection	Dadun. Depósito Académico Digital de la Universidad de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
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Sex dimorphism in the myocardial response to aortic stenosis

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